Ii-index zovavanyo lomsebenzi wokuxinana ziquka ixesha le-prothrombin (PT), ixesha le-activated partial thromboplastin (APTT), ixesha le-thrombin (TT), i-fibrinogen (FIB), ixesha lokuxinana (CT) kunye ne-International normalized ratio (INR), njl.njl., izinto ezininzi zinokukhethwa ukwenza iphakheji, ebizwa ngokuba yi-coagulation X item. Ngenxa yeendlela ezahlukeneyo zokufumanisa ezisetyenziswa zizibhedlele ezahlukeneyo, uluhlu lweereferensi nalo lwahlukile.

Ixesha le-PT-prothrombin

I-PT ibhekisa ekongezeni i-tissue factor (TF okanye i-tissue thromboplastin) kunye ne-Ca2+ kwi-plasma ukuze kuqaliswe inkqubo ye-extrinsic coagulation kunye nokujonga ixesha le-plasma lokujiya. I-PT yenye yezona vavanyo zovavanyo ezisetyenziswa kakhulu kwiklinikhi ukuvavanya umsebenzi wendlela ye-extrinsic coagulation. Ixabiso eliqhelekileyo lesalathiso yimizuzwana eli-10 ukuya kweli-14.

I-APTT - ixesha le-thromboplastin elingasebenziyo

I-APTT ifuna ukongeza i-XII factor activator, i-Ca2+, i-phospholipid kwi-plasma ukuze kuqaliswe indlela yokujiya kwe-plasma endogenous, kwaye kujongwe ixesha lokujiya kwe-plasma. I-APTT ikwayenye yezona vavanyo zovavanyo ezisetyenziswa kakhulu kwiklinikhi ukuvavanya umsebenzi wendlela yokujiya kwe-intrinsic. Ixabiso eliqhelekileyo lesalathiso yimizuzwana engama-32 ukuya kwengama-43.

INR - Umlinganiselo Oqhelekileyo Wehlabathi

I-INR ngamandla e-ISI omlinganiselo we-PT yesigulane esivavanyiweyo kwi-PT yolawulo oluqhelekileyo (ISI yi-international sensitivity index, kwaye i-reagent ilinganiswa ngumvelisi xa iphuma kwifektri). I-plasma efanayo yavavanywa ngee-reagents ezahlukeneyo ze-ISI kwiilabhoratri ezahlukeneyo, kwaye iziphumo zexabiso le-PT zahlukile kakhulu, kodwa amaxabiso e-INR alinganisiweyo ayefana, nto leyo eyenza iziphumo zafana. Ixabiso eliqhelekileyo lesalathiso yi-0.9 ukuya kwi-1.1.

Ixesha le-TT-thrombin

I-TT kukongeza i-thrombin eqhelekileyo kwi-plasma ukuze kufunyanwe inqanaba lesithathu lenkqubo yokujiya, ebonisa inqanaba le-fibrinogen kwi-plasma kunye nobungakanani bezinto ezifana ne-heparin kwi-plasma. Ixabiso eliqhelekileyo lesalathiso yimizuzwana eli-16 ukuya kweli-18.

I-FIB-fibrinogen

I-FIB kukongeza inani elithile le-thrombin kwi-plasma evavanyiweyo ukuguqula i-fibrinogen kwi-plasma ibe yi-fibrin, kwaye ubale umxholo we-fibrinogen ngokusebenzisa umgaqo we-turbidimetric. Ixabiso eliqhelekileyo lesalathiso yi-2 ukuya kwi-4 g/L.

Imveliso yokuchithwa kwe-FDP-plasma fibrin

I-FDP ligama eliqhelekileyo leemveliso zokubola eziveliswa emva kokuba i-fibrin okanye i-fibrinogen ibolile phantsi kwesenzo se-plasmin eveliswa ngexesha le-hyperfibrinolysis. Ixabiso eliqhelekileyo lesalathiso yi-1 ukuya kwi-5 mg/L.

Ixesha lokuxinana kwe-CT

I-CT ibhekisa kwixesha apho igazi liphuma emithanjeni yegazi lize lijiye kwi-vitro. Ngokuyintloko imisela ukuba izinto ezahlukeneyo zokujiya kwindlela yokujiya kwangaphakathi azikho na, nokuba umsebenzi wazo uqhelekile na, okanye ukuba kukho ukwanda kwezinto ezilwa nokujiya kwamalungu omzimba.