Ixesha le-Prothrombin (PT) libhekisela kwixesha elifunekayo kwi-plasma coagulation emva kokuguqulwa kweprothrombin kwi-thrombin emva kokongeza ukugqithisa kwe-tissue thromboplastin kunye nenani elifanelekileyo le-calcium ions kwi-plasma engasebenziyo yeplatelet.Ixesha eliphakamileyo leprothrombin (PT), oko kukuthi, ukongezwa kwexesha, kunokubangelwa izizathu ezahlukahlukeneyo ezifana ne-congenital abnormal coagulation factors, ifunyenwe izinto ezingaqhelekanga ze-coagulation, isimo esingaqhelekanga se-anticoagulation yegazi, njl. Uhlalutyo oluphambili lulandelayo:

1. Izinto ezingaqhelekanga zokuzala: Ukuveliswa okungaqhelekanga kwayo nayiphi na into ye-coagulation ye-I, II, V, VII, kunye ne-X emzimbeni iya kukhokelela kwixesha elide le-prothrombin (PT).Izigulane zinokongeza izinto zokudibanisa phantsi kwesikhokelo soogqirha ukuphucula le meko;

2. Izinto ezifunyenwe ngokungaqhelekanga ze-coagulation: isifo esibi esiqhelekileyo sesibindi, ukungabikho kwe-vitamin K, i-hyperfibrinolysis, ukusabalalisa i-intravascular coagulation, njl., ezi zinto ziya kubangela ukungabikho kwezinto zokudibanisa kwizigulane, okubangelwa ixesha elide le-prothrombin (PT).Izizathu ezithile kufuneka zichongwe kunyango olujoliswe kuyo.Ngokomzekelo, izigulane ezine-vitamin K ezinqongopheleyo zinokunyangwa nge-intravenous vitamin K1 supplementation ukukhuthaza ukubuyiswa kwexesha leprothrombin ngokuqhelekileyo;

3. Imeko ye-anticoagulation engaqhelekanga yegazi: kukho izinto ze-anticoagulant egazini okanye isigulane sisebenzisa izidakamizwa ze-anticoagulant, ezifana ne-aspirin kunye nezinye iziyobisi, ezineempembelelo ze-anticoagulant, eziza kuchaphazela indlela yokudibanisa kunye nokwandisa ixesha leprothrombin (PT).Kucetyiswa ukuba izigulane ziyeke iziyobisi ze-anticoagulant phantsi kwesikhokelo soogqirha kwaye zitshintshele kwezinye iindlela zonyango.

Ixesha leProthrombin (PT) ixesha elide ngaphezu kwemizuzwana ye-3 inokubaluleka kwekliniki.Ukuba iphezulu kakhulu kwaye ayidluli ixabiso eliqhelekileyo kwimizuzwana emi-3, inokuqwalaselwa ngokusondeleyo, kwaye unyango olukhethekileyo alufunwa ngokubanzi.Ukuba ixesha leprothrombin (PT) lide ixesha elide, kuyimfuneko ukuqhubela phambili ukufumanisa isizathu esithile kunye nokwenza unyango olujoliswe kuyo.