Ixesha le-Prothrombin (PT) libhekisa kwixesha elifunekayo lokujiya kwe-plasma emva kokuguqulwa kwe-prothrombin ibe yi-thrombin emva kokongeza i-thromboplastin engaphezulu kwezicubu kunye nomlinganiselo ofanelekileyo wee-calcium ions kwi-plasma engenazo iiplatelet. Ixesha eliphezulu le-prothrombin (PT), oko kukuthi, ukolulwa kwexesha, kunokubangelwa zizizathu ezahlukeneyo ezifana nezinto ezingaqhelekanga zokujiya kwe-congenital, izinto ezingaqhelekanga zokujiya ezifunyenweyo, imeko engaqhelekanga yokungajiyi kwegazi, njl. Uhlalutyo oluphambili lulandelayo:

1. Izinto ezingaqhelekanga zokujiya kwegazi ezizalwa nazo: Ukuveliswa okungaqhelekanga kwayo nayiphi na into ebangela ukujiya komzimba I, II, V, VII, kunye no-X kuya kukhokelela kwixesha elide le-prothrombin (PT). Izigulana zinokongeza izinto ezibangela ukujiya kwegazi phantsi kwesikhokelo soogqirha ukuphucula le meko;

2. Izinto ezingaqhelekanga ezifunyenwe ngokujiya kwegazi: isifo sesibindi esiqhelekileyo esinzima, ukungabikho kwe-vitamin K, i-hyperfibrinolysis, ukujiya kwemithambo yegazi esasazekileyo, njl.njl., ezi zinto ziya kukhokelela ekungafumaneki kwezinto ezijiyayo kwizigulana, nto leyo ekhokelela kwixesha elide le-prothrombin (PT). Izizathu ezithile kufuneka zichongwe ukuze kufumaneke unyango olujoliswe kulo. Umzekelo, izigulana eziswele i-vitamin K zinokunyangwa nge-intravenous vitamin K1 supplementation ukukhuthaza ukubuyela kwexesha le-prothrombin kwisiqhelo;

3. Imeko engaqhelekanga yokuthintela ukujiya kwegazi: kukho izinto ezithintela ukugabha kwegazi egazini okanye isigulane sisebenzisa amayeza athintela ukugabha kwegazi, njenge-aspirin kunye nezinye iziyobisi, ezinefuthe elithintela ukugabha kwegazi, eliya kuchaphazela indlela yokugabha igazi kwaye landise ixesha le-prothrombin (PT). Kucetyiswa ukuba izigulane ziyeke amayeza athintela ukugabha kwegazi phantsi kolwalathiso loogqirha kwaye zitshintshele kwezinye iindlela zonyango.

Ixesha le-prothrombin (PT) elonyuswa ngemizuzwana engaphezu kwemi-3 libalulekile kwiklinikhi. Ukuba liphezulu kakhulu kwaye alidluli ixabiso eliqhelekileyo kwimizuzwana emi-3, linokujongwa ngokusondeleyo, kwaye unyango olukhethekileyo alufuneki ngokubanzi. Ukuba ixesha le-prothrombin (PT) lilonyuswa ixesha elide kakhulu, kuyimfuneko ukufumanisa unobangela othile kwaye wenze unyango olujoliswe kulo.