Ma indekisi ekuyedza mashandiro ekuonda anosanganisira nguva yeprothrombin (PT), nguva yeropa yakabatidzwa (APTT), nguva yeropa (TT), fibrinogen (FIB), nguva yekuonda (CT) uye chiyero chepasi rose (INR), nezvimwewo, zvinhu zvakawanda zvinogona kusarudzwa kugadzira pakeji, iyo inonzi chinhu checoagulation X. Nekuda kwenzira dzakasiyana dzekuongorora dzinoshandiswa nezvipatara zvakasiyana, mareferensi akasiyanawo.

Nguva yePT-prothrombin

PT inoreva kuwedzera tissue factor (TF kana tissue thromboplastin) uye Ca2+ muplasma kuti vatange extrinsic coagulation system uye vaone nguva yekugwamba kweplasma. PT ndeimwe yemiedzo yekuongorora inoshandiswa zvakanyanya mukiriniki kuti vaongorore mashandiro e extrinsic coagulation pathway. Iyo yakajairika reference value imasekondi gumi kusvika gumi nemana.

APTT - nguva ye thromboplastin yakabatidzwa

APTT inofanira kuwedzera XII factor activator, Ca2+, phospholipid muplasma kuti itange nzira yeplasma yekuvharika kweropa, uye kuona nguva yekuvharika kweropa. APTT ndeimwe yemiedzo yekuongorora inoshandiswa zvakanyanya mukiriniki kuti iongorore mashandiro enzira yekuvharika kweropa. Iyo yakajairika imasekondi makumi matatu nemaviri kusvika makumi mana nematatu.

INR - Chiyero Chepasi Pose Chakajairika

INR isimba reISI rechiyero chePT yemurwere akaedzwa nePT yekutonga kwakajairika (ISI inhamba ye international sensitivity index, uye reagent inoongororwa nemugadziri painobva mufekitori). Plasma imwecheteyo yakaedzwa nema reagent akasiyana eISI mumarabhoritari akasiyana, uye mhedzisiro yePT value yaive yakasiyana zvikuru, asi ma INR values ​​​​akayerwa aive akafanana, izvo zvakaita kuti mhedzisiro ifanane. Iyo yakajairika reference value i0.9 kusvika 1.1.

Nguva yeTT-thrombin

TT kuwedzerwa kwe thrombin yakajairwa mu plasma kuti ione danho rechitatu remaitiro ekugwamba kweropa, zvichiratidza huwandu hwe fibrinogen mu plasma uye huwandu hwezvinhu zvakaita se heparin mu plasma. Kuverengerwa kwakajairika imasekondi gumi nematanhatu kusvika gumi nemasere.

FIB-fibrinogen

FIB ndeyekuwedzera huwandu hwakati hwe thrombin mu plasma yakaedzwa kuti ishandure fibrinogen mu plasma kuita fibrin, uye kuverenga huwandu hwe fibrinogen kuburikidza ne turbidimetric principle. Iyo yakajairika reference value i2 kusvika 4 g/L.

Chigadzirwa chekuparadza fibrin cheFDP-plasma

FDP izwi rekuti zvinhu zvinoora zvinogadzirwa mushure mekunge fibrin kana fibrinogen zvaora pasi pesimba replasmin rinogadzirwa panguva yehyperfibrinolysis. Chiyero chenguva dzose chinobva pa1 kusvika ku5 mg/L.

Nguva yeCT-coagulation

CT inoreva nguva iyo ropa rinobuda mutsinga dzeropa robva ragwamba mumuviri. Inonyanya kusarudza kana zvinhu zvakasiyana-siyana zvinoita kuti ropa rigwamba mutsinga dzemukati metsinga dzisashande zvakanaka, kana basa razvo rakajairika, kana kuti pane kuwedzera kwezvinhu zvinorwisa ropa kuti rigwamba.