Nguva yeprothrombin (PT) inoreva nguva inodiwa kuti plasma iunganidzwe mushure mekushandurwa kweprothrombin kuita thrombin mushure mekuwedzera tissue thromboplastin yakawandisa uye huwandu hwakakodzera hwecalcium ions kuita platelet-deficient plasma. Nguva yeprothrombin yakakwira (PT), kureva kuti, kuwedzera kwenguva, inogona kukonzerwa nezvikonzero zvakasiyana-siyana zvakaita se congenital abnormal coagulation factors, acquired abnormal coagulation factors, abnormal blood anticoagulation status, nezvimwewo. Ongororo huru ndeiyi inotevera:

1. Zvinhu zvisina kujairika zvekuvharika kweropa panguva yekuzvarwa: Kugadzirwa kusina kujairika kwechero chimwe chezvinhu zvinobatanidza ropa mumuviri I, II, V, VII, uye X kuchaita kuti prothrombin time (PT) iwedzere. Varwere vanogona kuwedzera zvinhu zvinobatanidza ropa mumuviri vachitungamirirwa navanachiremba kuti vagadzirise mamiriro aya;

2. Zvinhu zvisina kujairika zvekugwamba kweropa: chirwere chechiropa chakajairika, kushomeka kwevhitamini K, hyperfibrinolysis, kuvharika kweropa muropa, nezvimwewo, zvinhu izvi zvinotungamira kukushomeka kwezvinhu zvinovharika muvarwere, zvichikonzera nguva yakareba yeprothrombin (PT). Zvikonzero chaizvo zvinofanirwa kuzivikanwa kuti kurapwa kwacho kushandiswe. Semuenzaniso, varwere vane kushomeka kwevhitamini K vanogona kurapwa nekuwedzera vhitamini K1 mutsinga kuti nguva yeprothrombin idzokere pakare;

3. Mamiriro asina kujairika ekudzivirira ropa kuti risagwambe: pane zvinhu zvinorwisa ropa kuti riome kana murwere achishandisa mishonga inorwisa ropa kuti riome, yakadai seaspirin nemimwe mishonga, ine simba rekudzivirira ropa kuti riome, izvo zvinokanganisa mashandiro eropa kuti riome uye kuwedzera nguva yeprothrombin (PT). Zvinokurudzirwa kuti varwere varege kushandisa mishonga inorwisa ropa kuti riome vachitungamirirwa navanachiremba voshandisa dzimwe nzira dzekurapa.

Nguva yeprothrombin (PT) inowedzerwa nemasekondi anopfuura matatu ine kukosha kwekiriniki. Kana yakakwira zvakanyanya uye isingapfuure kukosha kwakajairika kwemasekondi matatu, inogona kutariswa zvakanyanya, uye kurapwa kwakakosha hakudiwi. Kana nguva yeprothrombin (PT) ikawedzerwa kwenguva yakareba, zvakakosha kuti uwane chikonzero chaicho uye uite kurapwa kwakanangana.