Nthawi ya prothrombin (PT) imatanthauza nthawi yomwe imafunika kuti magazi azigaya magazi pambuyo poti prothrombin yasinthidwa kukhala thrombin pambuyo powonjezera thromboplastin ya minofu ndi kuchuluka koyenera kwa ma calcium ions kukhala plasma yosowa ma platelet. Nthawi yayitali ya prothrombin (PT), kutanthauza kuti, kutalikitsa nthawiyo, kungayambitsidwe ndi zifukwa zosiyanasiyana monga congenital abnormal coagulation factors, acquired abnormal coagulation factors, abnormal blood anticoagulation status, etc. Kusanthula kwakukulu kuli motere:

1. Zinthu zachilendo zoberekera zotsekeka: Kupanga kosazolowereka kwa chimodzi mwa zinthu zolimbitsa thupi I, II, V, VII, ndi X m'thupi kumabweretsa nthawi yayitali ya prothrombin (PT). Odwala amatha kuwonjezera zinthu zolimbitsa thupi motsogozedwa ndi madokotala kuti akonze vutoli;

2. Zinthu zachilendo zopezeka m'magazi: matenda oopsa a chiwindi, kusowa kwa vitamini K, hyperfibrinolysis, kugawanika kwa magazi m'mitsempha, ndi zina zotero, zinthu izi zipangitsa kuti odwala asakhale ndi zinthu zogaya magazi, zomwe zimapangitsa kuti nthawi ya prothrombin ikhale yayitali (PT). Zifukwa zenizeni ziyenera kudziwika kuti alandire chithandizo. Mwachitsanzo, odwala omwe ali ndi vuto la vitamini K amatha kupatsidwa chithandizo cha intravenous vitamin K1 kuti athandize kuti nthawi ya prothrombin ibwerere mwakale;

3. Mkhalidwe wosayenera wa magazi woletsa magazi kuundana: pali zinthu zoletsa magazi kuundana m'magazi kapena wodwalayo akugwiritsa ntchito mankhwala oletsa magazi kuundana, monga aspirin ndi mankhwala ena, omwe ali ndi mphamvu zoletsa magazi kuundana, zomwe zimakhudza njira yolumikizira magazi ndikuwonjezera nthawi ya prothrombin (PT). Ndikofunikira kuti odwala asiye kugwiritsa ntchito mankhwala oletsa magazi kuundana motsogozedwa ndi madokotala ndikusintha njira zina zochizira.

Nthawi ya prothrombin (PT) yotalikitsidwa ndi masekondi opitilira atatu imakhala ndi tanthauzo lachipatala. Ngati ili yokwera kwambiri ndipo siipitirira mtengo wabwinobwino kwa masekondi atatu, imatha kuwonedwa bwino, ndipo chithandizo chapadera nthawi zambiri sichifunika. Ngati nthawi ya prothrombin (PT) yatalikitsidwa kwa nthawi yayitali, ndikofunikira kudziwa chifukwa chake ndikuchita chithandizo cholunjika.