He taurite te kaha o ngā pūnaha e rua, kia kore ai te toto e pupū, e toto nui rawa rānei.

Heoi, he maha ngā mate ka arahi ki te mahi rerekē o te pūnaha toto toto, me te kino hoki ki te intima o ngā uaua toto, ā, ka roa rawa, ka kore rānei e ranea te pūnaha fibrinolytic ki te whakarewa i ngā thrombus nā te noho pūmau o te toto.
Hei tauira, i roto i te mate pāwera uaua o te ngākau, ka pāngia ngā oko toto o te ngākau e te totohu. He tino kino te āhua o ngā oko toto, he maha ngā pakaru o te intima, ā, he stenosis, me te kore e rere te toto, kāore he huarahi hei whakarewa i te thrombus, ā, ka nui haere noa te thrombus.

Hei tauira, mō te hunga e takoto roa ana i runga i te moenga, ka puhoi te rere o te toto i roto i ngā waewae, ka pakaru te intima o ngā uaua toto, ā, ka puta he thrombus. Ka memeha tonu te thrombus, engari kāore i te tere te memeha, ka taka pea, ka rere anō ki roto i te uaua pūkahukahu i te taha o te pūnaha toto, ka mau ki roto i te uaua pūkahukahu, ā, ka puta he embolism pūkahukahu, he mea whakamate anō hoki.
I tēnei wā, kia noho haumaru ai ngā tūroro, me mahi hangai te thrombolysis me te werohanga i ngā rongoā hei whakatairanga i te thrombolysis, pērā i te "urokinase". Heoi, ko te tikanga me mahi te thrombolysis i roto i te wā poto o te thrombosis, pērā i roto i ngā haora e 6. Ki te roa te wā, e kore e memeha. Ki te whakanuia te whakamahinga o ngā rongoā thrombolytic i tēnei wā, ka puta pea he toto i ētahi atu wāhanga o te tinana.
Kāore e taea te whakarewa i te thrombus. Ki te kore e tino āraia, ka taea te whakamahi i te "stent" hei "huka i te whakatuwhera" i te oko toto kua āraia kia pai ai te rere o te toto.

Heoi, ki te aukatia te uaua toto mō te wā roa, ka puta he mate ischemic o ngā hanganga kiko nui. I tēnei wā, mā te "tāpae" i ētahi atu uaua toto ka taea te whakauru mai hei "whakamakuku" i tēnei wahi kiko kua ngaro te rere o te toto.

Ko te toto me te toto totoka, te toto toto me te toto toto, koinei te taurite ngawari e pupuri ana i ngā mahi pākia o te tinana. Haunga tēnā, he maha ngā taurite mohio i roto i te tinana tangata, pērā i te io atawhai me te io vagus, hei pupuri i te whakaohooho o te tangata me te kore e tino whakaohooho; ko te insulin me te glucagon te kaiwhakahaere i te taurite huka toto o te tangata; ko te calcitonin me te homoni parathyroid te kaiwhakahaere i te taurite konupūmā toto o te tangata.

Kia kore e taurite te taurite, ka puta mai ngā mate maha. Ko te nuinga o ngā mate o te tinana tangata ka puta mai i te ngaronga o te taurite.