Imbangela eyisisekelo

1. Ukulimala kwe-endothelial yenhliziyo nemithambo yegazi
Ukulimala kwe-endothelial cell yemithambo yegazi kuyimbangela ebaluleke kakhulu nevame kakhulu yokwakheka kwe-thrombus, futhi kuvame kakhulu kwi-rheumatic and infective endocarditis, izilonda ze-atherosclerotic plaque ezinzima, izindawo zokulimala kwe-arteriovenous ezibuhlungu noma ezivuvukalayo, njll. Kukhona futhi i-hypoxia, i-shock, i-sepsis kanye ne-bacterial endotoxins ezibangela izifo eziningi emzimbeni wonke.
Ngemva kokulimala kwesikhumba, i-collagen ngaphansi kwe-endothelium ivuselela inqubo yokujiya, okubangela ukujiya kwemithambo yegazi okusabalele, kanye nokwakheka kwe-thrombus ku-microcirculation yomzimba wonke.

2. Ukugeleza kwegazi okungavamile
Ngokuyinhloko kubhekisela ekunciphiseni ukugeleza kwegazi kanye nokukhiqizwa kwama-eddies ekugelezeni kwegazi, njll., kanye nezinto ezisebenza ngokujiya kanye ne-thrombin zifinyelela izinga elidingekayo ukuze kujiyane endaweni yasendaweni, okusiza ekwakhekeni kwe-thrombus. Phakathi kwazo, imithambo ithambekele kakhulu ekujiyani, okuyinto evame kakhulu ezigulini ezinesifo senhliziyo, izifo ezingamahlalakhona kanye nokuphumula kombhede ngemva kokuhlinzwa. Ngaphezu kwalokho, ukugeleza kwegazi enhliziyweni nasemithanjeni kuyashesha, futhi akulula ukwakha i-thrombus. Kodwa-ke, lapho ukugeleza kwegazi ku-atrium yangakwesobunxele, i-aneurysm, noma igatsha lomthambo wegazi kuhamba kancane futhi kwenzeka i-eddy current ngesikhathi se-mitral valve stenosis, ithambekele nasekujiyani.

3. Ukwanda kokujiya kwegazi
Ngokuvamile, ama-platelet kanye nezinto ezibangela ukujiya kwegazi ziyanda, noma umsebenzi wohlelo lwe-fibrinolytic uyancipha, okuholela esimweni sokujiya kwegazi ngokweqile egazini, esivame kakhulu ezimweni ze-hypercoagulable ezizuzwe njengefa kanye nezitholwe nge-hypercoagulable.

4. Isimo sofuzo sokuqhekeka kwegazi
Kuhlobene nokukhubazeka kwe-coagulation factor okuzuzwe njengefa, ukukhubazeka kokuzalwa kweprotheni C kanye neprotheni S, njll. Phakathi kwazo, ukuguquka kwezakhi zofuzo okuvame kakhulu kwe-factor V, izinga lokuguquka kwalesi sakhi sofuzo lingafinyelela ku-60% ezigulini ezine-deep vein thrombosis ephindaphindayo.

5. Isimo esitholiwe sokujiya kwegazi
Kuvame ukubonakala kumdlavuza we-pancreatic, umdlavuza wamaphaphu, umdlavuza webele, umdlavuza we-prostate, umdlavuza wesisu kanye nezinye izimila eziyingozi ezisakazeke kakhulu, ezibangelwa ukukhishwa kwezinto ezibangela ukugabha kwegazi ngamaseli omdlavuza; kungabuye kwenzeke nasekulimaleni okukhulu, ukusha okukhulu, ukuhlinzwa okukhulu noma ngemva kokubeletha Uma kwenzeka ukulahlekelwa igazi elikhulu, nasezimweni ezifana nomfutho wegazi ophakeme wokukhulelwa, i-hyperlipidemia, i-coronary atherosclerosis, ukubhema, kanye nokukhuluphala.