Thrombosis ke ts'ebetso eo ho eona mali a phallang a phallang 'me a fetoha lesela la mali, joalo ka cerebral artery thrombosis (e bakang cerebral infarction), thrombosis e tebileng ea methapo e ka tlaase, joalo-joalo.leqeba la madi le bopehileng sebakeng se itseng sa mothapo wa madi le falla ho bapa le phallo ya madi mme le koalletsoe mothapong o mong wa madi.Mokhoa oa ho embolisa o bitsoa embolism.The deep vein thrombosis ea maoto le matsoho a ka tlaase e oa, ea falla, 'me e kenngoa teronkong ea pulmonary artery' me e baka pulmonary embolism.;Leqeba la mali le bakang embolism le bitsoa embolus ka nako ena.
Bophelong ba letsatsi le leng le le leng, lesela la mali le ntšoa ka mor'a hore nko e emise;moo leqeba le lemetseng, ka linako tse ling leqeba le ka utluoa, leo hape e leng thrombus;mme myocardial infarction e bakoa ke ho sitisa phallo ea mali ha mothapo oa pelo o sa tsebeng pelo o thijoa ke leqeba la mali Ischemic necrosis ea myocardium.
Tlas'a maemo a fisioloji, karolo ea thrombosis ke ho emisa ho tsoa mali.Ho lokisoa ha lisele le litho leha e le life ho tlameha ho emisa ho tsoa mali pele.Hemophilia ke coagulopathy e bakoang ke khaello ea lintho tse kopanyang.Ho thata ho theha thrombus karolong e lemetseng 'me ha e khone ho emisa ka katleho ho tsoa mali le ho baka mali.Bongata ba hemostatic thrombosis bo hlaha 'me bo teng ka ntle ho mothapo oa mali kapa moo mothapo oa mali o robehileng.
Haeba lesela la mali le hlaha ka har’a mothapo oa mali, phallo ea mali ka har’a mothapo oa mali oa thibeloa, phallo ea mali ea fokotseha, kapa esita le phallo ea mali ea sitisoa.Haeba thrombosis e hlaha methapong, e tla baka ischemia ea setho / mesifa esita le necrosis, e kang myocardial infarction, cerebral infarction, le necrosis e ka tlaase / ho khaoloa.Thrombus e entsoeng ka har'a methapo e tebileng ea lipheletsong tse ka tlaase ha e ame feela ho phalla ha mali a venous ka pelong 'me e baka ho ruruha ha likarolo tse tlaase, empa hape e oela ka tlaase ho vena cava, atrium e nepahetseng le ventricle e nepahetseng ho kena le ho kenngoa chankaneng. pulmonary artery, e lebisang ho embolism ea pulmonary.Mafu a nang le litekanyetso tse phahameng tsa ho shoa.
Ho qala ha thrombosis
Maemong a mangata, sehokelo sa pele sa thrombosis ke kotsi, e ka ba ts'oaetso, ho buuoa, ho phatloha ha letlapa ka har'a methapo, kapa esita le tšenyo ea ho qetela e bakoang ke tšoaetso, ho itšireletsa mafung le lintho tse ling.Ts'ebetso ena ea thrombus e qalisoang ke kotsi e bitsoa "exogenous coagulation system".Maemong a 'maloa, stasis ea mali kapa ho lieha ho phalla ha mali ho ka boela ha qala ts'ebetso ea thrombosis, e leng mokhoa oa ho kopanya, o bitsoang endogenous coagulation system.
Hemostasis ea mantlha
Hang ha kotsi e ama methapo ea mali, liplatelete li khomarela pele ho etsa lesela le le leng ho koahela leqeba, ebe li kenngoa tšebetsong hore li kopane ho etsa clumps, e leng platelet thrombi.Tshebetso ena kaofela e bitsoa primary hemostasis.
Hemostasis ea bobeli
Kotsi e ntša ntho ea coagulation e bitsoang tissue factor, e qalang tsamaiso ea endogenous coagulation ho hlahisa thrombin ka mor'a ho kena maling.Thrombin ha e le hantle ke sesosa se fetolang protheine ea coagulation maling, ke hore, fibrinogen hore e be fibrin., Ts'ebetso eohle e bitsoa bobeli ba hemostasis.
"Tšebelisano e phethahetseng"Thrombosis
Nakong ea thrombosis, mohato oa pele oa hemostasis (platelet adhesion, activation le aggregation) le mohato oa bobeli oa hemostasis (tlhahiso ea thrombin le sebopeho sa fibrin) li sebelisana hammoho.Hemostasis ea mohato oa bobeli e ka etsoa feela ka mokhoa o tloaelehileng ka pel'a li-platelet, 'me thrombin e entsoeng e tsoela pele ho sebetsa liplatelete.Bobeli ba sebetsa 'moho' me ba sebetsa 'moho ho phethela tšebetso ea thrombosis.
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