Chikonzero chikuru

1. Kukuvara kwemwoyo nemidziyo yeropa
Kukuvara kwemasero etsinga dzeropa ndicho chikonzero chikuru uye chinowanzo konzera kuumbwa kweropa, uye chinowanzoitika mu rheumatic ne infective endocarditis, maronda akakomba e atherosclerotic plaque, nzvimbo dzakakuvara dze trauma kana inflammatory arteriovenous, nezvimwewo. Kunewo hypoxia, shock, sepsis uye bacterial endotoxins zvinokonzera zvirwere zvakasiyana-siyana mumuviri wese.
Mushure mekukuvara kweganda, collagen iri pasi pe endothelium inomutsa maitiro ekugwamba kweropa, zvichikonzera kupararira kweropa muropa, uye thrombus inoumbwa mu microcirculation yemuviri wese.

2. Kuyerera kweropa kusina kujairika
Zvinonyanya kureva kudzikira kwekuyerera kweropa uye kugadzirwa kwe eddies mukuyerera kweropa, nezvimwewo, uye activated coagulation factors uye thrombin zvinosvika pakuwanda kunodiwa kuti coagulation iite munzvimbo yemuno, izvo zvinoita kuti thrombus iumbwe. Pakati pazvo, mitsipa inonyanya kubatwa ne thrombus, iyo inonyanya kuwanikwa muvarwere vane chirwere chemwoyo, chirwere chisingaperi uye mushure mekuvhiyiwa. Pamusoro pezvo, kuyerera kweropa mumoyo netsinga dzeropa kunokurumidza, uye hazvisi nyore kugadzira thrombus. Zvisinei, kana kuyerera kweropa mu left atrium, aneurysm, kana bazi re blood vessel kunonoka uye eddy current inoitika panguva ye mitral valve stenosis, inowanzobatwa ne thrombosis.

3. Kuwedzera kweropa rinogwamba
Kazhinji, maplatelet nezvinhu zvinosunga ropa zvinowedzera, kana kuti mashandiro e fibrinolytic system anoderera, zvichiita kuti ropa rive ne hypercoagulable state, iyo inowanzoonekwa muropa rine nhaka uye rinowanikwa rine hypercoagulable states.

4. Kugadzika kweropa zvakanyanya
Izvi zvine chekuita nekusakwana kwezvikamu zveropa, zvikanganiso zvekuberekwa nazvo zveprotein C neprotein S, nezvimwewo. Pakati pavo, kushanduka kwemajini echinhu chinonzi V, mwero wekushanduka kwemajini aya unogona kusvika 60% muvarwere vane thrombosis yetsinga yakadzama inodzokororwa.

5. Mamiriro ekuti ropa rikwanise kuungana
Inowanzoonekwa mukenza yepancreatic, kenza yemapapu, kenza yemazamu, kenza yeprostate, kenza yemudumbu nedzimwe bundu dzakapararira zvakanyanya, dzinokonzerwa nekuburitswa kweprocoagulant factors nemasero ekenza; inogonawo kuitika mukukuvara kwakanyanya, kutsva kwakanyanya, kuvhiyiwa kukuru kana mushure mekusununguka Kana ropa rakawanda rikarasikirwa, uye mumamiriro ezvinhu akadai sepamuviri une hypertension, hyperlipidemia, coronary atherosclerosis, kusvuta, uye kufuta.