Nyob rau hauv cov xwm txheej ntawm lub cev, lub luag haujlwm ntawm thrombosis yog kom tsis txhob los ntshav. Kev kho cov ntaub so ntswg thiab cov kabmob yuav tsum ua ntej kom tsis txhob los ntshav. Hemophilia yog ib qho kev coagulopathy uas tshwm sim los ntawm tsis muaj cov tshuaj coagulation. Nws nyuaj rau tsim thrombus hauv qhov raug mob thiab tsis tuaj yeem tiv thaiv kev los ntshav thiab ua rau los ntshav. Feem ntau cov hemostatic thrombosis tsim thiab muaj nyob sab nraum cov hlab ntsha lossis qhov twg cov hlab ntsha tawg.

Yog tias cov ntshav txhaws tsim nyob rau hauv cov hlab ntsha, cov ntshav ntws hauv cov hlab ntsha raug thaiv, cov ntshav ntws raug txo qis, lossis txawm tias cov ntshav ntws raug cuam tshuam. Yog tias thrombosis tshwm sim hauv cov hlab ntsha, nws yuav ua rau cov khoom nruab nrog / cov nqaij ischemia thiab txawm tias necrosis, xws li myocardial infarction, cerebral infarction, thiab qis qis necrosis / amputation. Cov thrombus tsim nyob rau hauv cov leeg ntshav tob ntawm qis qis tsis yog tsuas yog cuam tshuam rau cov ntshav ntws mus rau hauv lub plawv thiab ua rau o ntawm qis qis, tab sis kuj poob tawm los ntawm inferior vena cava, sab xis atrium thiab sab xis ventricle nkag mus rau hauv pulmonary artery, ua rau pulmonary embolism. Cov kab mob uas muaj feem pua ​​​​​​ntawm kev tuag ntau.

Kev pib mob thrombosis

Feem ntau, qhov pib ntawm kev mob thrombosis yog kev raug mob, uas tuaj yeem yog kev raug mob, phais, plaque tawg hauv cov hlab ntsha, lossis txawm tias endothelial puas tsuaj los ntawm kev kis kab mob, kev tiv thaiv kab mob thiab lwm yam. Cov txheej txheem ntawm kev tsim thrombus no pib los ntawm kev raug mob hu ua exogenous coagulation system. Hauv ob peb qhov xwm txheej, ntshav tsis txav lossis qeeb ntawm cov ntshav ntws kuj tuaj yeem pib cov txheej txheem ntawm thrombosis, uas yog ib txoj hauv kev sib cuag, hu ua endogenous coagulation system.

Kev hemostasis thawj zaug

Thaum qhov raug mob cuam tshuam rau cov hlab ntsha, cov platelets ua ntej lo rau ua ib txheej los npog qhov txhab, thiab tom qab ntawd raug ua kom sib sau ua ke los ua cov pawg, uas yog platelet thrombi. Tag nrho cov txheej txheem no hu ua thawj hemostasis.

Kev hemostasis theem ob

Qhov kev raug mob tso tawm cov tshuaj coagulation hu ua tissue factor, uas pib lub endogenous coagulation system los tsim thrombin tom qab nkag mus rau hauv cov ntshav. Thrombin yog qhov tseeb yog ib qho catalyst uas hloov cov coagulation protein hauv cov ntshav, uas yog, fibrinogen mus rau hauv fibrin. , Tag nrho cov txheej txheem hu ua secondary hemostasis.

"Kev Sib Txuas Lus Zoo Tag Nrho"Kev mob ntshav txhaws

Hauv cov txheej txheem ntawm thrombosis, thawj theem ntawm hemostasis (platelet adhesion, activation thiab aggregation) thiab theem ob ntawm hemostasis (thrombin ntau lawm thiab fibrin tsim) koom tes nrog ib leeg. Theem ob hemostasis tsuas yog ua tau raws li qhov xwm txheej thaum muaj platelets, thiab cov thrombin tsim ntxiv ua rau cov platelets ua haujlwm. Ob qho tib si ua haujlwm ua ke thiab ua haujlwm ua ke kom ua tiav cov txheej txheem ntawm thrombosis..