I-ESR, eyaziwa nangokuthi izinga lokusatshalaliswa kwe-erythrocyte, ihlobene nokubonakala kwe-plasma, ikakhulukazi amandla okuhlangana phakathi kwama-erythrocyte. Amandla okuhlangana phakathi kwamaseli abomvu egazi makhulu, izinga lokusatshalaliswa kwe-erythrocyte liyashesha, futhi okuphambene nalokho. Ngakho-ke, izinga lokusatshalaliswa kwe-erythrocyte livame ukusetshenziswa ngokwezokwelapha njengesibonakaliso sokuhlanganiswa kwama-erythrocyte. I-ESR iyisivivinyo esingaqondile futhi ayinakusetshenziswa yodwa ukuthola noma yisiphi isifo.

I-ESR isetshenziswa kakhulu emtholampilo kulezi zifo ezilandelayo:

1. Ukuze kubonwe izinguquko kanye nemiphumela yokwelapha yesifo sofuba kanye nomkhuhlane wamathambo, i-ESR esheshayo ikhombisa ukuthi lesi sifo siyaphinda futhi siyasebenza; lapho lesi sifo sithuthuka noma siphela, i-ESR iyalulama kancane kancane. Iphinde isetshenziswe njengereferensi ekuxilongweni.

2. Ukuxilongwa okuhlukile kwezifo ezithile, njenge-myocardial infarction kanye ne-angina pectoris, umdlavuza wesisu kanye nesilonda sesisu, isisindo somdlavuza we-pelvic kanye ne-ovarian cyst engeyona inkimbinkimbi. I-ESR yanda kakhulu kweyokuqala, kuyilapho eyesibili yayivamile noma ikhuphuke kancane.

3. Ezigulini ezine-myeloma eminingi, inani elikhulu le-globulin engajwayelekile livela ku-plasma, futhi izinga lokushiswa kwe-erythrocyte lishesha kakhulu. Izinga lokushiswa kwe-erythrocyte lingasetshenziswa njengenye yezinkomba ezibalulekile zokuxilonga.

4. I-ESR ingasetshenziswa njengesibonakaliso selabhorethri somsebenzi we-rheumatoid arthritis. Lapho isiguli silulama, izinga lokushiswa kwe-erythrocyte lingancipha. Kodwa-ke, ukubonwa kwezokwelapha kubonisa ukuthi kwezinye iziguli ezine-rheumatoid arthritis, izinga lokushiswa kwe-erythrocyte lingancipha (hhayi ngokujwayelekile) kuyilapho izimpawu nezimpawu ezifana nobuhlungu bamalunga, ukuvuvukala nokuqina kwasekuseni kuthuthuka, kodwa kwezinye iziguli, yize izimpawu zamalunga omtholampilo sezinyamalele ngokuphelele, kodwa izinga lokushiswa kwe-erythrocyte alizange lehle, futhi ligcinwe lisezingeni eliphezulu.