ESR, yomwe imadziwikanso kuti erythrocyte sedimentation rate, imagwirizana ndi kukhuthala kwa plasma, makamaka mphamvu yosonkhana pakati pa erythrocytes. Mphamvu yosonkhana pakati pa maselo ofiira a magazi ndi yayikulu, kuchuluka kwa erythrocyte sedimentation rate ndi yachangu, ndipo mosemphanitsa. Chifukwa chake, kuchuluka kwa erythrocyte sedimentation rate nthawi zambiri kumagwiritsidwa ntchito ngati chizindikiro cha kusonkhana pakati pa erythrocyte. ESR ndi mayeso osadziwika bwino ndipo sangagwiritsidwe ntchito yokha kuzindikira matenda aliwonse.

ESR imagwiritsidwa ntchito kwambiri pa matenda awa:

1. Kuti muwone kusintha ndi zotsatira zake zochiritsa chifuwa chachikulu ndi malungo a nyamakazi, kuchuluka kwa ESR komwe kumawonjezeka kumasonyeza kuti matendawa akubwereranso ndipo akugwira ntchito; matendawa akapita patsogolo kapena kusiya, ESR imachira pang'onopang'ono. Imagwiritsidwanso ntchito ngati chizindikiro cha matenda.

2. Kuzindikira matenda osiyanasiyana monga matenda a mtima ndi angina pectoris, khansa ya m'mimba ndi zilonda zam'mimba, khansa ya m'chiuno ndi chotupa cha ovarian chosavuta. ESR inawonjezeka kwambiri m'magazi oyamba, pomwe yachiwiri inali yabwinobwino kapena inakwera pang'ono.

3. Kwa odwala omwe ali ndi myeloma yambiri, kuchuluka kwa globulin kosazolowereka kumawonekera mu plasma, ndipo kuchuluka kwa erythrocyte sedimentation rate kumawonjezeka kwambiri. Kuchuluka kwa erythrocyte sedimentation rate kungagwiritsidwe ntchito ngati chimodzi mwa zizindikiro zofunika kwambiri zodziwira matenda.

4. ESR ingagwiritsidwe ntchito ngati chizindikiro cha labotale cha ntchito ya nyamakazi. Wodwala akachira, kuchuluka kwa erythrocyte sedimentation kumatha kuchepa. Komabe, zomwe zapezeka kuchipatala zikuwonetsa kuti mwa odwala ena omwe ali ndi nyamakazi ya rheumatoid, kuchuluka kwa erythrocyte sedimentation kumatha kuchepa (osati mwachizolowezi) pomwe zizindikiro ndi zizindikiro monga kupweteka kwa mafupa, kutupa ndi kuuma kwa m'mawa zimakula, koma mwa odwala ena, ngakhale zizindikiro za matenda a mafupa zatha kwathunthu, koma kuchuluka kwa erythrocyte sedimentation sikunatsikebe, ndipo kwakhalabe pamlingo wapamwamba.