I-Coagulopathy idla ngokubhekisa kwisifo sokungasebenzi kakuhle kwe-coagulation, esibangelwa zizinto ezahlukeneyo ezikhokelela ekungafumaneki kwezinto ezibangela ukujiya okanye ukungasebenzi kakuhle kwe-coagulation, okubangela uthotho lokopha okanye ukopha. Ingohlulwa ibe zizifo zokuzalwa kunye nezofuzo zokungasebenzi kakuhle kwe-coagulation, izifo ezifunyenweyo ze-Acquired coagulation.

1. Iingxaki zokubola kwesisu ezibangelwa kukuzalwa: ngenxa yezinto ezibangelwa kukuzalwa ezifana neziphene zezakhi zofuzo, ngokuqhelekileyo i-X chromosome inelifa eliphindaphindayo, i-hemophilia eqhelekileyo, iimpawu zeklinikhi kukuphuma kwegazi ngesiquphe, i-hematoma, i-dysphagia, njl. Ngovavanyo lwelabhoratri, kunokufunyaniswa ukuba i-thromboplastin yesigulana ayiveliswanga kakuhle, kwaye phantsi kwesikhokelo sikagqirha, i-vitamin K1, iipilisi ze-phensulfame kunye nezinye iziyobisi zinokongezwa ukukhuthaza ukubola kwegazi;

2. Isifo sokungakwazi ukuqina kwemithambo yegazi: sibhekisa ekungakwazini ukuqina kwemithambo yegazi okubangelwa ziziyobisi, izifo okanye iityhefu, njl. Ezona zixhaphakileyo kukungasebenzi kakuhle kwemithambo yegazi okubangelwa kukungabikho kwevithamini K kunye nesifo sesibindi. Kubalulekile ukunyanga izinto eziphambili ngokwengcebiso kagqirha. Ukuba sibangelwa ziziyobisi, iyeza kufuneka lincitshiswe okanye limiswe ngokufanelekileyo, emva koko izinto zokuqina kwegazi ezifana nevithamini K zinokufakwa ngokwemeko yokopha, kwaye utofelo-gazi lungasetyenziswa. Ukuba i-thrombus ibangelwa kukungasebenzi kakuhle kwemithambo yegazi, unyango lwe-anticoagulant, olufana ne-heparin sodium kunye nezinye iziyobisi ze-anticoagulant, luyafuneka.