Which departments are coagulation analyzer mainly used for?


Author: Succeeder    

The blood coagulation analyzer is an instrument used for routine blood coagulation testing. It is a necessary testing equipment in the hospital. It is used to detect the hemorrhagic tendency of blood coagulation and thrombosis. What is the application of this instrument in various departments?

Among the testing items of the blood coagulation analyzer, PT, APTT, TT, and FIB are four routine testing items for blood coagulation. Among them, PT reflects the levels of blood coagulation factors II, V, VII, and X in the blood plasma, and is the most important part of the exogenous coagulation system. Sensitive and commonly used screening test; APTT reflects the levels of coagulation factors V, VIII, IX, XI, XII, fibrinogen, and fibrinolytic activity in plasma, and is a commonly used screening test for endogenous systems; TT measurement mainly reflects whether the blood Presence of abnormal anticoagulant substances: FIB is a glycoprotein that, under hydrolysis by thrombin, finally forms insoluble fibrin to stop bleeding.

1. Orthopedic patients are mostly patients with fractures caused by various reasons, most of which require surgical treatment. After fractures, due to musculoskeletal damage, part of blood vessels rupture, intravascular and cell exposure activate blood coagulation mechanism, platelet aggregation, and fibrinogen formation. achieve the purpose of hemostasis. Activation of the late fibrinolytic system, thrombolysis, and tissue repair. These processes all affect the data of routine coagulation testing before and after surgery, so timely detection of various coagulation indexes is of great significance for predicting and treating abnormal bleeding and thrombosis in fracture patients.

Abnormal bleeding and thrombosis are common complications in surgery. For patients with abnormal coagulation routine, the cause of the abnormality should be found before surgery to ensure the success of the surgery.

2. DIC is the most prominent bleeding disease caused by obstetrics and gynecology, and the abnormal rate of FIB is significantly increased. It is of great clinical significance to know the abnormal changes of blood coagulation indexes in time, and can detect and prevent DIC as soon as possible.

3. Internal medicine has a wide variety of diseases, mainly cardiovascular diseases, digestive system diseases, ischemic and hemorrhagic stroke patients. In routine coagulation examinations, the abnormal rates of PT and FIB are relatively high, mainly due to anticoagulation, thrombolysis and other treatments. Therefore, it is particularly important to do routine coagulation examinations and other thrombus and hemostasis detection items to provide a basis for formulating reasonable treatment plans.

4. Infectious diseases are mainly acute and chronic hepatitis, and PT, APTT, TT, and FIB of acute hepatitis are all within the normal range. In chronic hepatitis, cirrhosis, and severe hepatitis, with the aggravation of liver damage, the ability of the liver to synthesize coagulation factors decreases, and the abnormal detection rate of PT, APTT, TT, and FIB increases significantly. Therefore, routine detection of blood coagulation and dynamic observation are of great significance for clinical prevention and treatment of bleeding and prognosis estimation.

Therefore, accurate routine examination of coagulation function is helpful to provide a basis for clinical diagnosis and treatment. Blood coagulation analyzers should be rationally used in various departments to play the greatest role.