Yimiphi iminyango i-coagulation analyzer esetshenziselwa kakhulu?


Umbhali: Olandelayo   

I-blood coagulation analyzer iyithuluzi elisetshenziselwa ukuhlola ukuhlangana kwegazi okujwayelekile.Kuyimishini yokuhlola edingekayo esibhedlela.Isetshenziselwa ukuthola ukuthambekela ukopha kwe-blood coagulation kanye ne-thrombosis.Iyini ukusetshenziswa kwaleli thuluzi eminyangweni ehlukahlukene?

Phakathi kwezinto ezihlolwayo ze-blood coagulation analyzer, i-PT, i-APTT, i-TT, ne-FIB kukhona izinto ezine ezijwayelekile zokuhlola ukuhlangana kwegazi.Phakathi kwazo, i-PT ikhombisa amazinga we-blood coagulation factor II, V, VII, no-X ku-plasma yegazi, futhi iyingxenye ebaluleke kakhulu ye-exogenous coagulation system.Ukuhlolwa kokuhlola okubucayi nokuvame ukusetshenziswa;I-APTT ibonisa amazinga ezinto zokuhlanganisa i-V, VIII, IX, XI, XII, fibrinogen, kanye nomsebenzi we-fibrinolytic ku-plasma, futhi iwukuhlolwa kokuhlola okuvame ukusetshenziswa kwezinhlelo ze-endogenous;Ukulinganisa kwe-TT kukhombisa ngokuyinhloko ukuthi ingabe igazi Ubukhona bezinto ezingajwayelekile ze-anticoagulant: I-FIB iyi-glycoprotein okuthi, ngaphansi kwe-hydrolysis nge-thrombin, ekugcineni yakhe i-fibrin engenakuncibilika ukuze imise ukopha.

1. Iziguli zamathambo ngokuvamile ziyiziguli eziphuka ngenxa yezizathu ezihlukahlukene, eziningi zazo ezidinga ukwelashwa kokuhlinzwa.Ngemuva kokwephuka, ngenxa yokulimala kwemisipha namathambo, ingxenye yemithambo yegazi iyaphuka, ukuchayeka kwe-intravascular kanye neseli kusebenze indlela yokuhlangana kwegazi, ukuhlangana kweplatelet, kanye nokwakheka kwe-fibrinogen.ukufeza injongo ye-hemostasis.Ukwenza kusebenze uhlelo lwe-fibrinolytic sekwephuzile, i-thrombolysis, nokulungiswa kwezicubu.Lezi zinqubo zonke zithinta idatha yokuhlolwa kwe-coagulation evamile ngaphambi nangemuva kokuhlinzwa, ngakho ukutholakala ngesikhathi kwezinkomba ezihlukahlukene zokuhlangana kubaluleke kakhulu ekubikezeleni nasekwelapheni ukopha okungavamile kanye ne-thrombosis ezigulini eziphukayo.

Ukopha okungavamile kanye ne-thrombosis yizinkinga ezivamile ekuhlinzeni.Ezigulini ezinohlelo lwe-coagulation olungavamile, imbangela yokungajwayelekile kufanele itholakale ngaphambi kokuhlinzwa ukuze kuqinisekiswe impumelelo yokuhlinzwa.

2. I-DIC yisifo esopha esivelele kakhulu esibangelwa ukubelethisa kanye ne-gynecology, futhi izinga elingavamile le-FIB lenyuka kakhulu.Kubaluleke kakhulu emtholampilo ukwazi izinguquko ezingavamile zezinkomba zokuhlangana kwegazi ngesikhathi, futhi kungathola futhi kuvimbele i-DIC ngokushesha ngangokunokwenzeka.

3. Umuthi wangaphakathi unezinhlobonhlobo zezifo, ikakhulukazi izifo zenhliziyo, izifo zesistimu yokugaya ukudla, iziguli ze-ischemic kanye ne-hemorrhagic stroke.Ekuhlolweni kwe-coagulation evamile, amazinga angavamile e-PT ne-FIB aphezulu kakhulu, ikakhulukazi ngenxa ye-anticoagulation, i-thrombolysis nokunye ukwelashwa.Ngakho-ke, kubaluleke kakhulu ukwenza ukuhlolwa kwe-coagulation evamile kanye nezinye izinto zokuthola i-thrombus kanye ne-hemostasis ukuze unikeze isisekelo sokwenza izinhlelo zokwelashwa ezinengqondo.

4. Izifo ezithathelwanayo ngokuyinhloko ziyi-hepatitis eyingozi futhi engapheli, kanti i-PT, APTT, TT, ne-FIB ye-hepatitis eyingozi konke kungaphakathi kwebanga elivamile.Ku-hepatitis engapheli, i-cirrhosis, nesifo sokusha kwesibindi esibi kakhulu, ngokubhebhetheka kokulimala kwesibindi, ikhono lesibindi lokuhlanganisa izici ze-coagulation liyehla, futhi izinga lokutholwa okungavamile kwe-PT, APTT, TT, ne-FIB landa kakhulu.Ngakho-ke, ukutholakala okujwayelekile kokujiya kwegazi kanye nokubhekwa okushukumisayo kubaluleke kakhulu ekuvimbeleni emtholampilo nasekwelapheni ukopha kanye nesilinganiso sokubikezela.

Ngakho-ke, ukuhlolwa okunembile okujwayelekile komsebenzi we-coagulation kuyasiza ukunikeza isisekelo sokuxilongwa nokwelashwa komtholampilo.Ama-analyzer e-blood coagulation kufanele asetshenziswe ngokunengqondo eminyangweni ehlukahlukene ukuze adlale indima enkulu kakhulu.