Ngemva kokwakheka kwe-thrombosis, isakhiwo sayo siyashintsha ngaphansi kwesenzo sesistimu ye-fibrinolytic kanye nokushaqeka kokugeleza kwegazi kanye nokuvuselelwa komzimba.
Kunezinhlobo ezintathu eziyinhloko zezinguquko zokugcina ku-thrombus:
1. Ncibilikisa, ncibilikisa, munca
Ngemva kokuba i-thrombus yakheke, i-fibrin ekuyo imunca inani elikhulu le-plasmin, ukuze i-fibrin eku-thrombus ibe yi-polypeptide encibilikayo bese incibilika, bese i-thrombus ithambe. Ngesikhathi esifanayo, ngoba ama-neutrophils aku-thrombus ayahlakazeka futhi akhiphe ama-enzyme e-proteolytic, i-thrombus nayo ingancibilika futhi ithambe.
I-thrombus encane iyancibilika futhi ibe uketshezi, futhi ingamuncwa ngokuphelele noma igezwe yigazi ngaphandle kokushiya umkhondo.
Ingxenye enkulu ye-thrombus iyathamba futhi iwe kalula ngokugeleza kwegazi ibe yi-embolus. I-emboli ivimba umthambo wegazi ohambisanayo nokugeleza kwegazi, okungabangela i-embolism, kuyilapho ingxenye esele ihlelekile.
2. Ukwenziwa Kwemishini Nokwenziwa Kabusha Kwemithombo Yamanzi
Ama-thrombi amakhulu akulula ukuwancibilikisa nokuwamunca ngokuphelele. Ngokuvamile, zingakapheli izinsuku ezimbili kuya kwezingu-3 ngemva kokwakheka kwe-thrombus, izicubu ze-granulation ziyakhula zisuka ku-intima yemithambo yegazi eyonakele lapho i-thrombus inamathele khona, bese kancane kancane zithatha indawo ye-thrombus, ebizwa ngokuthi inhlangano ye-thrombus.
Uma i-thrombus ihlelekile, i-thrombus iyancipha noma incibilike kancane, futhi kuvame ukwakheka umfantu ngaphakathi kwe-thrombus noma phakathi kwe-thrombus nodonga lwemithambo yegazi, futhi ubuso bumbozwe amaseli e-endothelial emithambo yegazi akhulayo, futhi ekugcineni kwakheka imithambo yegazi eyodwa noma eziningana ezincane ezixhumana nomthambo wegazi wokuqala. Ukuvuselelwa kokugeleza kwegazi kubizwa ngokuthi ukuvuselelwa kwe-thrombus.
3. Ukwakheka kwe-Calcification
Inani elincane le-thrombi elingenakuncibilika noma lihlelwe ngokuphelele lingabangelwa usawoti we-calcium, lakha amatshe aqinile akhona emithanjeni yegazi, abizwa ngokuthi ama-phlebolith noma ama-arteriolith.
Umphumela wamahlule egazi emzimbeni
I-Thrombosis inemiphumela emibili emzimbeni.
1. Ohlangothini oluhle
I-Thrombosis yakheka emthanjeni wegazi oqhekekile, onomthelela we-hemostatic; i-thrombosis yemithambo yegazi emincane ezungeze i-foci yokuvuvukala ingavimbela ukusabalala kwamagciwane abangela izifo kanye nobuthi.
2. Okubi
Ukwakheka kwe-thrombus emthanjeni wegazi kungavimba umthambo wegazi, okubangela ischemia yezicubu nezitho zomzimba kanye nokuphazamiseka kwegazi;
I-Thrombosis iyenzeka ku-valve yenhliziyo. Ngenxa yokuhleleka kwe-thrombus, i-valve iba yi-hypertrophic, inciphe, inamathele, futhi iqine, okuholela esifweni senhliziyo se-valvular futhi kuthinte ukusebenza kwenhliziyo;
I-thrombus kulula ukuyiwa bese yakha i-embolus, ehambisana nokugeleza kwegazi futhi yakhe i-embolism kwezinye izingxenye, okuholela ekushayweni okukhulu kwemithambo yegazi;
Ukwanda okukhulu kwe-microthrombosis ku-microcirculation kungabangela ukuphuma kwegazi okukhulu kanye nokushaqeka.
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