Bayan an kafa thrombosis, tsarinsa yana canzawa a ƙarƙashin aikin tsarin fibrinolytic da bugun jini da sake farfadowa na jiki.

Akwai manyan nau'ikan 3 na canje-canje na ƙarshe a cikin thrombus:

1. Tausasa, narke, sha

Bayan da thrombus ya samu, fibrin da ke cikinsa yana shan plasmin mai yawa, ta yadda fibrin da ke cikin thrombus ya zama polypeptide mai narkewa ya narke, kuma thrombus yana yin laushi.A lokaci guda, saboda neutrophils a cikin thrombus tarwatsa da kuma saki proteolytic enzymes, thrombus kuma za a iya narkar da da taushi.

Karamin thrombus ya narke ya yi ruwa, kuma za a iya shafe shi gaba daya ko kuma ya wanke shi ta hanyar jini ba tare da barin wata alama ba.

Mafi girman ɓangaren thrombus yana yin laushi kuma cikin sauƙi ya faɗi ta hanyar jini ya zama embolus.Emboli yana toshe madaidaicin jini tare da kwararar jini, wanda zai iya haifar da embolism, yayin da aka tsara sauran ɓangaren.

2. Mechanization da Recanalization

Manyan thrombi ba su da sauƙin narkewa kuma su sha gaba ɗaya.Yawancin lokaci, a cikin kwanaki 2 zuwa 3 bayan samuwar thrombus, granulation nama yana tsiro daga lalacewar jijiyar intima inda aka haɗa thrombus, kuma a hankali ya maye gurbin thrombus, wanda ake kira kungiyar thrombus.
Lokacin da thrombus ya shirya, thrombus yana raguwa ko kuma ya narke, kuma sau da yawa yakan haifar da fissure a cikin thrombus ko tsakanin thrombus da bangon jirgin ruwa, kuma saman yana rufe ta hanyar yaduwar kwayoyin endothelial na jijiyoyi, kuma a karshe daya ko da yawa ƙananan jini. waɗanda ke sadarwa tare da asalin jigon jini suna samuwa.Recanalization na kwararar jini ana kiransa recanalization na thrombus.

3. Calcification

Ƙananan adadin thrombi waɗanda ba za a iya narkar da su gaba ɗaya ko tsara su ba na iya haɓakawa da ƙila su ta hanyar salts calcium, suna samar da duwatsu masu ƙarfi da ke cikin tasoshin jini, wanda ake kira phleboliths ko arterioliths.