Thrombin Time Kit (TT)

TT inoreva nguva yekuvhara ropa mushure mekuwedzera yakagadziriswa thrombin kuplasma.Mune yakajairika coagulation nzira, iyo inogadzirwa thrombin inoshandura fibrinogen kuita fibrin, iyo inogona kuratidzwa neTT.Nekuti fibrin (proto) degradation products (FDP) inogona kuwedzera TT, vamwe vanhu vanoshandisa TT sechiratidzo chekuongorora chefibrinolytic system.

Clinical kukosha:

(1) TT yakareba (kupfuura 3s kupfuura kutonga kwakajairika) heparin uye heparinoid zvinhu zvinowedzera, zvakadai se lupus erythematosus, chirwere chechiropa, chirwere chetsvo, etc. Low (kwete) fibrinogenemia, fibrinogenemia isina kukwana.

(2) FDP yakawedzera: yakadai seDIC, primary fibrinolysis uye zvichingodaro.

Nguva yakareba yethrombin (TT) inoonekwa mukuderera kweplasma fibrinogen kana kukanganisa kwemaitiro;kliniki yekushandiswa kweheparin, kana kuwedzera heparin-yakafanana neanticoagulants muchirwere chechiropa, chirwere chetsvo uye systemic lupus erythematosus;hyperfunction ye fibrinolytic system.Yakapfupika nguva yethrombin inoonekwa muhupo hwe calcium ions muropa, kana ropa rine acidic, nezvimwe.

Thrombin nguva (TT) inoratidzira yeanticoagulant substance mumuviri, saka kuwedzera kwayo kunoratidza hyperfibrinolysis.Chiyero ndiyo nguva yekugadzirwa kwefibrin mushure mekuwedzera yakagadziriswa thrombin, saka mune yakaderera (hapana) chirwere chefibrinogen, DIC uye Yakareba muhupo hweheparinoid zvinhu (zvakadai seheparin therapy, SLE uye chirwere chechiropa, nezvimwewo).Kupfupisa kweTT hakuna kukosha kwekiriniki.

Normal Range:

Yakajairika kukosha ndeye 16~18s.Kupfuura zvakajairika kutonga kweanopfuura 3s hazvina kunaka.

Cherechedza:

(1) Plasma haifanire kudarika 3h pane tembiricha yekamuri.

(2) Disodium edetate uye heparin haifaniri kushandiswa se anticoagulants.

(3) Pakupera kwekuedza, nzira ye test tube inobva pane yekutanga coagulation apo turbidity inoratidzika;iyo girazi ndiro nzira yakavakirwa pakukwanisa kutsamwisa fibrin filaments

Zvirwere zvinoenderana:

Lupus erythematosus