Mushure mekunge thrombosis yaumbwa, chimiro chayo chinoshanduka pasi pesimba re fibrinolytic system uye kuvhunduka kweropa uye kudzoreredzwa kwemuviri.

Kune mhando nhatu huru dzekuchinja kwekupedzisira mu thrombus:

1. Nyorosa, nyungudutsa, nyudza

Mushure mekunge thrombus yaumbwa, fibrin iri mairi inonwisa huwandu hwakawanda hweplasmin, zvekuti fibrin iri mu thrombus inova polypeptide inonyungudika yonyungudika, uye thrombus inonyorova. Panguva imwe chete, nekuti ma neutrophils ari mu thrombus anoputsika oburitsa ma enzymes eproteolytic, thrombus inogonawo kunyungudika yonyorova.

Kamuviri kadiki kanonyunguduka koita mvura, uye kanogona kunyungudutswa zvachose kana kusukwa neropa pasina kusiya kana kadonhwe.

Chikamu chikuru che thrombus chinonyoroveswa uye chinodonha nyore nyore nekuyerera kweropa kuti chive embolus. Emboli inovhara tsinga yeropa inoenderana nekuyerera kweropa, izvo zvinogona kukonzera embolism, nepo chikamu chasara chakarongeka.

2. Kugadzira Michina uye Kugadzirisazve

Matumbu makuru haasi nyore kunyungudika nekunyungudika zvachose. Kazhinji, mukati memazuva maviri kusvika matatu mushure mekuumbwa kweropa, granulation tissue inokura kubva muvascular intima yakakuvara uko thrombus yakabatana, uye zvishoma nezvishoma inotsiva thrombus, iyo inonzi thrombus organization.
Kana thrombus yarongeka, thrombus inodzikira kana kunyungudika zvishoma, uye mutswe unowanzo umbwa mukati me thrombus kana pakati pe thrombus nemadziro etsinga, uye pamusoro payo pakafukidzwa nemasero e endothelial eropa ari kuwanda, uye pakupedzisira tsinga imwe kana dzakawanda diki dzeropa dzinotaurirana netsinga yeropa yekutanga dzinoumbwa. Kudzokororwa kwekuyerera kweropa kunonzi kudzokororwa kwe thrombus.

3. Kugadziriswa kweCalcification

Madonhwe mashoma eropa asinganyunguduke zvachose kana kurongeka anogona kuunganidzwa nekusanganiswa necalcium salts, zvichigadzira matombo akaoma ari mutsinga dzeropa, anonzi phleboliths kana arterioliths.