Chida cha Nthawi ya Thrombin (TT)

TT imatanthauza nthawi yothira magazi pambuyo powonjezera thrombin yokhazikika mu plasma. Mu njira yodziwika bwino yothira magazi, thrombin yopangidwa imasintha fibrinogen kukhala fibrin, yomwe imatha kuwonetseredwa ndi TT. Chifukwa fibrin (proto) degradation products (FDP) imatha kukulitsa TT, anthu ena amagwiritsa ntchito TT ngati mayeso owunikira dongosolo la fibrinolytic.

Kufunika kwachipatala:

(1) TT imatalikitsidwa (kuposa masekondi atatu kuposa momwe munthu amalamulira) zinthu za heparin ndi heparinoid zimawonjezeka, monga lupus erythematosus, matenda a chiwindi, matenda a impso, ndi zina zotero. Fibrinogenemia yotsika (yopanda) komanso fibrinogenemia yosadziwika bwino.

(2) FDP yawonjezeka: monga DIC, primary fibrinolysis ndi zina zotero.

Nthawi yayitali ya thrombin (TT) imawoneka mu kuchepa kwa fibrinogen m'magazi kapena zolakwika m'mapangidwe; kugwiritsa ntchito heparin kuchipatala, kapena kuchuluka kwa mankhwala oletsa magazi oundana ngati heparin pa matenda a chiwindi, matenda a impso ndi lupus erythematosus; kugwira ntchito mopitirira muyeso kwa dongosolo la fibrinolytic. Nthawi yochepa ya thrombin imawoneka mukakhala ndi ma calcium ions m'magazi, kapena magazi ali ndi acid, ndi zina zotero.

Nthawi ya Thrombin (TT) ndi chizindikiro cha mankhwala oletsa magazi kuundana m'thupi, kotero kufalikira kwake kumasonyeza hyperfibrinolysis. Kuyeza ndi nthawi yopangira fibrin pambuyo powonjezera thrombin yokhazikika, kotero mu matenda otsika (opanda) fibrinogen, DIC ndi Kutalika kwa nthawi yayitali pamaso pa zinthu za heparinoid (monga chithandizo cha heparin, SLE ndi matenda a chiwindi, ndi zina zotero). Kufupikitsa kwa TT sikuli ndi tanthauzo lililonse lachipatala.

Mtundu Wabwinobwino:

Mtengo wabwinobwino ndi masekondi 16 mpaka 18. Kupitirira muyeso wabwinobwino kwa masekondi opitilira 3 sikwachilendo.

Zindikirani:

(1) Plasma sayenera kupitirira maola atatu kutentha kwa chipinda.

(2) Disodium edetate ndi heparin siziyenera kugwiritsidwa ntchito ngati mankhwala oletsa magazi kuundana.

(3) Pamapeto pa kuyesa, njira ya chubu choyesera imachokera pa kuuma koyamba pamene kutayikira kumawonekera; njira ya mbale yagalasi imachokera pa kuthekera koyambitsa ulusi wa fibrin

Matenda okhudzana ndi izi:

Lupus erythematosus