The Traditional Clinical Application of D-Dimer

Author: Succeeder    

1.VTE troubleshooting diagnosis:
D-Dimer detection combined with clinical risk assessment tools can be efficiently used for the exclusion diagnosis of deep vein thrombosis (DVT) and pulmonary embolism (PE).When used for thrombus exclusion, there are certain requirements for D-Dimer reagents, methodology, etc. According to the D-Dimer industry standard, combined with prior probability, the negative prediction rate is required to be ≥ 97%, and the sensitivity is required to be ≥ 95%.
2. Auxiliary diagnosis of disseminated intravascular coagulation (DIC):
The typical manifestation of DIC is hyperfibrinolysis, and the detection of hyperfibrinolysis plays an important role in the DIC scoring system. Clinically, it has been shown that D-Dimer in DIC patients increases significantly (more than 10 times). In diagnostic guidelines or consensus for DIC both domestically and internationally, D-Dimer is considered one of the laboratory indicators for diagnosing DIC, and it is recommended to carry out FDP in conjunction to effectively improve the diagnostic efficiency of DIC. The diagnosis of DIC cannot rely solely on a single laboratory indicator and a single examination result to draw conclusions. It needs to be comprehensively analyzed and dynamically monitored in conjunction with the patient's clinical manifestations and other laboratory indicators in order to make a judgment.