Mgbe e guzobere thrombosis, nhazi ya na-agbanwe n'okpuru ọrụ nke sistemụ fibrinolytic na ujo ọbara na mmeghari ahụ nke ahụ.

E nwere ụdị mgbanwe atọ dị mkpa na thrombus:

1. Mee ka ọ dị nro, gbazee, mịpụta

Mgbe e guzobere thrombus, fibrin dị na ya na-amịkọrọ nnukwu plasmin, nke mere na fibrin dị na thrombus ga-aghọ polypeptide a na-agbaze agbaze ma gbazee, thrombus na-adịkwa nro. N'otu oge ahụ, n'ihi na neutrophils dị na thrombus na-agbaze ma na-ewepụta enzymes proteolytic, thrombus nwekwara ike ịgbaze ma mee ka ọ dị nro.

Obere thrombus ahụ na-agbaze ma na-agbaze mmiri mmiri, ọbara ọbara nwekwara ike ịmịkọrọ ya ma ọ bụ sachaa ya kpamkpam n'ahapụghị ihe ọ bụla.

Akụkụ ka ukwuu nke thrombus na-adị nro ma na-ada ngwa ngwa site na mmiri ọbara na-asọ wee ghọọ embolus. Emboli ahụ na-egbochi arịa ọbara kwekọrọ na mmiri ọbara, nke nwere ike ibute embolism, ebe akụkụ fọdụrụ na-ahazi.

2. Nhazi na Nhazigharị

Ọ dịghị mfe ịgbaze ma mikpuo thrombi ndị buru ibu kpamkpam. Ọtụtụ mgbe, n'ime ụbọchị abụọ ruo atọ mgbe e guzobere thrombus, anụ ahụ granulation na-eto site na intima nke akwara mebiri emebi ebe thrombus jikọtara, ma jiri nwayọọ nwayọọ dochie thrombus, nke a na-akpọ thrombus organization.
Mgbe thrombus ahụ haziri, thrombus ahụ na-ebelata ma ọ bụ na-agbaze nke ọma, a na-etolitekwa mgbawa n'ime thrombus ma ọ bụ n'etiti thrombus na mgbidi arịa ahụ, a na-ekpuchikwa elu ya site na mkpụrụ ndụ endothelial vascular na-amụba, n'ikpeazụkwa, otu ma ọ bụ ọtụtụ obere arịa ọbara ndị na-ekwurịta okwu na arịa ọbara mbụ ahụ na-etolite. A na-akpọ recanalization nke ọbara na-asọgharị ọzọ nke thrombus.

3. Calcific

Nnu calcium nwere ike ime ka obere thrombi nke a na-apụghị ịgbaze ma ọ bụ hazie kpamkpam pụta, wee mepụta nkume siri ike dị n'ime arịa ọbara, nke a na-akpọ phleboliths ma ọ bụ arterioliths.