Bayan an kafa thrombosis, tsarinsa yana canzawa ƙarƙashin aikin tsarin fibrinolytic da girgiza kwararar jini da sake farfaɗowar jiki.

Akwai manyan nau'ikan canje-canje guda 3 na ƙarshe a cikin thrombus:

1. Yi laushi, narke, sha

Bayan an samar da thrombus, fibrin da ke cikinsa yana shan plasmin mai yawa, ta yadda fibrin da ke cikin thrombus zai zama polypeptide mai narkewa ya narke, thrombus kuma ya yi laushi. A lokaci guda, saboda neutrophils da ke cikin thrombus suna wargajewa kuma suna fitar da enzymes na proteolytic, thrombus kuma za a iya narkar da su da kuma laushi.

Ƙaramin thrombus ɗin yana narkewa ya kuma sha ruwa, kuma jinin zai iya sha ko ya wanke shi gaba ɗaya ba tare da barin wata alama ba.

Babban ɓangaren thrombus yana laushi kuma cikin sauƙi yana faɗuwa ta hanyar kwararar jini ya zama embolus. Emboli ɗin yana toshe jijiyoyin jini masu dacewa da kwararar jini, wanda zai iya haifar da embolism, yayin da sauran ɓangaren kuma an tsara shi.

2. Injini da Sake Tsaftacewa

Manyan ƙwayoyin cuta ba su da sauƙin narkewa da sha gaba ɗaya. Yawanci, cikin kwana 2 zuwa 3 bayan samuwar ƙwayoyin cuta, ƙwayoyin cuta suna girma daga lalacewar jijiyoyin jini inda aka haɗa ƙwayoyin cuta, kuma a hankali suna maye gurbin ƙwayoyin cuta, wanda ake kira ƙungiyar ƙwayoyin cuta.
Idan aka tsara thrombus, thrombus ɗin zai ragu ko kuma ya narke kaɗan, kuma sau da yawa akwai tsagewa a cikin thrombus ko tsakanin thrombus da bangon jijiyoyin jini, kuma saman yana rufe da ƙwayoyin endothelial na jijiyoyin jini masu yaɗuwa, kuma a ƙarshe ana samun ƙananan jijiyoyin jini guda ɗaya ko da yawa waɗanda ke hulɗa da jijiyoyin jini na asali. Ana kiran sake fasalin kwararar jini sake fasalin thrombus.

3. Kalkuleta

Ƙaramin adadin thrombi wanda ba za a iya narkar da shi gaba ɗaya ko tsara shi ba zai iya haifar da kuma daidaita shi ta hanyar gishirin calcium, wanda ke samar da duwatsu masu tauri da ke cikin jijiyoyin jini, waɗanda ake kira phleboliths ko arterioliths.