Ingxaki yokujiya kwegazi ibeka esichengeni ubomi, kuba ukuphazamiseka kokuqina kwegazi kungenxa yezizathu ezahlukeneyo ezibangela ukuphazamiseka kokusebenza komzimba womntu.Emva kokungasebenzi kakuhle kwe-coagulation, uluhlu lweempawu zokuphuma kwegazi luya kwenzeka.Ukuba kukho ukopha okukhulu kwe-intracranial, kukho ingozi enkulu yobomi.Ngenxa yokuba zininzi izifo ezibangelwa kukungasebenzi kakuhle kwe-coagulation, ikliniki eqhelekileyo yi-hemophilia A, i-hemophilia B, i-vascular hemophilia, ukunqongophala kwevithamin K, ukusasaza imithambo yegazi kwivithamin Ezi zifo zinokubangela ukujija kwezifo ezingasebenziyo.Ukuba sisigulana esine-hemophilia eqatha, kukho utyekelo lokopha okucacileyo ngokwalo.Emva kokwenzakala okungephi, kulula ukubangela ukopha.Ukuba izigulana ezinehemophilia emandla kakhulu ziphathwa kumonzakalo, kulula ukubangela ukopha kakhulu kwe-craniocerebral, nto leyo ebeka emngciphekweni ubomi besigulane.Ukongeza, imithambo yegazi ebukhali yangaphakathi i-coagulation, ngenxa yokusetyenziswa kunye nokungasebenzi kakuhle kwe-coagulation yezizathu ezahlukeneyo zokudityaniswa, kunye nokopha kakhulu, okukhokelela ekufeni kwangoko komguli.