Ka taea e te thrombin te whakatairanga i te toto totoka, te aukati i te toto, ā, ka taea hoki te whakatairanga i te whakaora patunga me te whakatika kiko.

He matū whākōkī nui te thrombin i roto i te tukanga whakapūpū toto, ā, he whākōkī matua i hurihia tuatahitia hei fibrin i roto i te fibrin. Ina pakaru ngā oko toto, ka puta te glycrase i raro i te mahi a ngā pereti toto me ngā pūtau endothelial vascular, ka whakatairanga i te kohikohinga o ngā pereti toto me te thrombosis, ā, ka mutu te hemostasis. Hei tāpiri, ka taea hoki e te coordinase te whakatairanga i te whakaora patunga me te whakatika kiko, he matū whākōkī tino nui i roto i te whakatika kiko.

Me mōhio ko te nui rawa o te whakahohenga o te thrombin ka pā mai pea ngā raruraru pēnei i te thrombosis me te mate pūnaha toto. Nō reira, me whai tonu i ngā tohutohu a te tākuta me te horopeta o ngā rongoā i te wā e whakamahi ana i ngā rongoā e pā ana ki te coordinase hei karo i ngā pānga kino me ngā pānga taha.

Ko te mahi a te fibrinogen i te tīmatanga ko te whakatairanga i te kohikohinga o ngā pereti toto i roto i te toto totoka. I te tīmatanga he pūmua nui te fibrinogen i roto i te tukanga toto totoka. Ko tana mahi matua ko te toto totoka me te hemostasis, me te whai wāhi ki te hanga pereti toto. Ko te uara noa o te fibrinogen he 2-4g/L. Ko te pikinga o te taumata taketake o te fibrin e pā tata ana ki te putanga mai o ngā mate toto totoka. Ko te pikinga o te pikinga o te fibrin ka puta pea i ngā āhuatanga ā-tinana, pēnei i te haputanga me te pakeketanga, i ngā āhuatanga mate rānei, pēnei i te toto toto tiketike, te mate huka, te mate ngakau atherosclerotic coronary.

Ka heke te taumata o te fibrin, ka puta pea i ngā mate ate, pērā i te cirrhosis me te hepatitis ūkui. Me haere ngā tūroro ki te hōhipera kia tirotirohia i te wā tika, ā, me rongoā rātou i raro i te arataki a te tākuta.