I-Thrombin inokukhuthaza ukuhlangana kwegazi, idlale indima ekunqandeni ukopha, kwaye inokukhuthaza ukuphiliswa kwenxeba kunye nokulungiswa kwezicubu.

I-Thrombin yinto ebalulekileyo ye-enzyme kwinkqubo ye-coagulation yegazi, kwaye yi-enzyme ephambili eyayiguqulelwe ekuqaleni ibe yi-fibrin kwi-fibrin.Xa imithwalo yegazi yonakalisiwe, i-glycrase yenziwa phantsi kwesenzo seplatelet kunye neeseli ze-vascular endothelial, ukukhuthaza i-platelet agglomeration kunye ne-thrombosis, ngaloo ndlela imisa i-hemostasis.Ukongeza, ulungelelwaniso lunokukhuthaza ukuphiliswa kwenxeba kunye nokulungiswa kwezicubu, nto leyo eyimfuneko ye-enzyme ekulungisweni kwezicubu.

Kufuneka kuqatshelwe ukuba ukusetyenziswa ngokugqithiseleyo kwe-thrombin kunokubangela iingxaki ezifana ne-thrombosis kunye nesifo senhliziyo.Ngoko ke, kuyimfuneko ukulandela ngokungqongqo iingcebiso zogqirha kunye nomthamo wamachiza xa usebenzisa i-coordinase-related drug ukuphepha ukusabela okubi kunye nemiphumo emibi.

Umsebenzi we-fibrinogen ekuqaleni wawuyimpembelelo yokukhuthaza i-platelet agglomeration kwi-coagulation yegazi.I-Fibrinogen ekuqaleni yayiyiprotheni ebalulekileyo kwinkqubo ye-coagulation.Umsebenzi wayo oyintloko yi-coagulation kunye ne-hemostasis, kunye nokuthatha inxaxheba kwimveliso yeeplatelet.Ixabiso eliqhelekileyo le-fibrinogen yi-2-4g / L.Ukuphakama kwinqanaba lokuqala le-fibrin lihambelana ngokusondeleyo nesehlo sezifo ze-thrombotic.Ukunyuka kokunyuka kwe-fibrin kunokubangelwa yizinto zomzimba, ezifana nokukhulelwa kwexesha elide kunye nobudala, okanye izinto ze-pathological, ezifana noxinzelelo lwegazi, isifo sikashukela, isifo senhliziyo se-coronary atherosclerotic.

Umgangatho wefibrin uyancipha, onokuthi ubangelwe zizifo zesibindi, ezifana ne-cirrhosis kunye ne-acute hepatitis.Izigulane kufuneka ziye esibhedlele ukuze zixilongwe kwangethuba kwaye zibanyange phantsi kolwalathiso lukagqirha.