Thrombin e ka khothaletsa ho hoama ha mali, ea bapala karolo ea ho emisa ho tsoa ha mali, hape e ka khothaletsa pholiso ea maqeba le tokiso ea lisele.

Thrombin ke ntho ea bohlokoa ea enzyme tšebetsong ea ho hoama ha mali, 'me ke enzyme ea bohlokoa eo qalong e ileng ea fetoloa fibrin ho fibrin.Ha methapo ea mali e senyehile, glycrase e hlahisoa tlasa ts'ebetso ea liplatelete le lisele tsa vascular endothelial, tse khothalletsang ho kopana ha platelet le thrombosis, ka hona ho emisa hemostasis.Ntle le moo, coordinase e ka khothaletsa pholiso ea maqeba le tokiso ea lisele, e leng ntho ea bohlokoahali ea enzyme tokisong ea lisele.

Hoa lokela ho hlokomeloa hore ts'ebetso e feteletseng ea thrombin e ka boela ea baka mathata a kang thrombosis le lefu la pelo.Ka hona, hoa hlokahala ho latela ka tieo keletso ea ngaka le litekanyetso tsa lithethefatsi ha u sebelisa lithethefatsi tse amanang le coordinase ho qoba liketso tse mpe le litla-morao.

Mosebetsi oa fibrinogen qalong e ne e le phello ea ho khothaletsa ho kopana ha liplatelete ho coagulation ea mali.Fibrinogen qalong e ne e le protheine ea bohlokoa ts'ebetsong ea coagulation.Mosebetsi oa eona o ka sehloohong ke coagulation le hemostasis, le ho kenya letsoho tlhahisong ea liplatelete.Boleng bo tloaelehileng ba fibrinogen ke 2-4g/L.Ho phahama ha boemo ba pele ba fibrin ho amana haufi-ufi le ho hlaha ha mafu a thrombotic.Ho phahama ha fibrin ho ka bakoa ke lintlha tsa 'mele, tse kang ho ima ha morao le lilemo, kapa mabaka a pathological, a kang khatello ea mali, lefu la tsoekere, lefu la pelo la coronary atherosclerotic.

Boemo ba fibrin bo fokotsehile, bo ka ’nang ba bakoa ke mafu a sebete, a kang lefu la ho thatafala ha sebete le lefu la sebete le matla.Bakuli ba lokela ho ea sepetlele ho ea hlahlojoa ka nako le ho ba phekola tlas'a tataiso ea ngaka.