Hauv lub neej, tib neeg yuav muaj kev sib tsoo thiab los ntshav qee zaum. Feem ntau, yog tias qee qhov txhab tsis kho, cov ntshav yuav maj mam coagulate, tsis los ntshav ntawm nws tus kheej, thiab thaum kawg tawm cov ntshav tawv. Vim li cas qhov no? Cov tshuaj twg tau ua lub luag haujlwm tseem ceeb hauv cov txheej txheem no? Tom ntej no, cia peb tshawb nrhiav kev paub txog kev coagulation ntshav ua ke!

Raws li peb txhua tus paub, cov ntshav yeej ib txwm ncig hauv tib neeg lub cev raws li lub plawv thawb kom thauj cov pa oxygen, protein, dej, electrolytes thiab carbohydrates uas lub cev xav tau. Raws li qhov xwm txheej ib txwm muaj, cov ntshav ntws hauv cov hlab ntsha. Thaum cov hlab ntsha puas lawm, lub cev yuav tsum tsis txhob los ntshav thiab txhaws los ntawm ntau yam kev ua xua. Kev coagulation thiab hemostasis ib txwm ntawm tib neeg lub cev feem ntau nyob ntawm cov qauv thiab kev ua haujlwm ntawm phab ntsa hlab ntsha, kev ua haujlwm ib txwm ntawm cov yam ntxwv coagulation, thiab qhov zoo thiab ntau ntawm cov platelets zoo.

Feem ntau, cov ntshav platelets raug teeb tsa raws phab ntsa sab hauv ntawm cov hlab ntsha capillaries kom tswj tau qhov ruaj khov ntawm cov hlab ntsha. Thaum cov hlab ntsha raug puas tsuaj, kev sib zog ua ntej tshwm sim, ua rau cov phab ntsa ntawm cov hlab ntsha hauv qhov chaw puas tsuaj ze rau ib leeg, ua rau qhov txhab me me thiab qeeb qeeb cov ntshav ntws. Tib lub sijhawm, cov ntshav platelets lo rau, sib sau ua ke thiab tso tawm cov ntsiab lus ntawm qhov chaw puas tsuaj, tsim cov ntshav platelet thrombus hauv zos, thaiv qhov txhab. Kev hemostasis ntawm cov hlab ntsha thiab cov ntshav platelets hu ua thawj hemostasis, thiab cov txheej txheem ntawm kev tsim cov fibrin clot ntawm qhov chaw raug mob tom qab ua haujlwm ntawm lub kaw lus coagulation los thaiv qhov txhab hu ua lub tshuab hemostatic thib ob.

Tshwj xeeb, cov ntshav coagulation txhais tau hais tias cov ntshav hloov ntawm lub xeev ntws mus rau lub xeev gel tsis ntws. Coagulation txhais tau hais tias ntau yam coagulation factors raug ua haujlwm los ntawm enzymolysis, thiab thaum kawg thrombin raug tsim los ua fibrin clot.Cov txheej txheem coagulation feem ntau suav nrog peb txoj kev, endogenous coagulation pathway, exogenous coagulation pathway thiab common coagulation pathway.

1) Txoj kev coagulation endogenous yog pib los ntawm coagulation factor XII los ntawm kev sib cuag. Los ntawm kev ua kom muaj zog thiab kev sib xyaw ntawm ntau yam coagulation factors, prothrombin thaum kawg hloov mus ua thrombin. Thrombin hloov fibrinogen mus ua fibrin kom ua tiav lub hom phiaj ntawm kev coagulation ntshav.

2) Txoj kev coagulation sab nraud yog hais txog kev tso tawm ntawm nws tus kheej cov ntaub so ntswg, uas xav tau lub sijhawm luv luv rau kev coagulation thiab teb sai.

Cov kev tshawb fawb tau qhia tias txoj kev coagulation endogenous thiab txoj kev coagulation exogenous tuaj yeem ua haujlwm sib koom ua ke thiab ua haujlwm sib koom ua ke.

3) Txoj kev coagulation feem ntau yog hais txog theem coagulation ntawm endogenous coagulation system thiab exogenous coagulation system, uas feem ntau suav nrog ob theem ntawm thrombin tiam thiab fibrin tsim.

Qhov hu ua hemostasis thiab cov hlab ntsha puas tsuaj, uas ua rau txoj kev coagulation sab nraud ua haujlwm. Lub luag haujlwm ntawm txoj kev coagulation endogenous tam sim no tsis meej heev. Txawm li cas los xij, nws paub tseeb tias txoj kev coagulation ntshav endogenous tuaj yeem ua haujlwm thaum tib neeg lub cev kov cov khoom siv dag, uas txhais tau tias cov khoom siv biological tuaj yeem ua rau cov ntshav coagulation hauv tib neeg lub cev, thiab qhov xwm txheej no kuj tau dhau los ua qhov teeb meem loj rau kev cog cov khoom siv kho mob hauv tib neeg lub cev.

Tej yam tsis zoo lossis tej yam cuam tshuam rau cov ntshav coagulation lossis tej yam txuas hauv cov txheej txheem coagulation yuav ua rau muaj tej yam tsis zoo lossis tej yam tsis ua haujlwm hauv tag nrho cov txheej txheem coagulation. Pom tau tias cov ntshav coagulation yog ib qho txheej txheem nyuaj thiab nyuaj heev hauv tib neeg lub cev, uas ua lub luag haujlwm tseem ceeb hauv kev tswj peb lub neej.