Ukujiya kwegazi ngokuvamile akukho kungakhathaliseki ukuthi kuhle noma kubi. Ukujiya kwegazi kunesikhathi esijwayelekile. Uma kushesha kakhulu noma kuhamba kancane, kuzoba yingozi emzimbeni womuntu.

Ukujiya kwegazi kuzoba ngaphakathi kwebanga elithile elijwayelekile, ukuze kungabangela ukopha nokwakheka kwe-thrombus emzimbeni womuntu. Uma ukujiya kwegazi kushesha kakhulu, ngokuvamile kubonisa ukuthi umzimba womuntu usesimweni sokujiya kakhulu, futhi izifo zenhliziyo nemithambo yegazi zivame ukwenzeka, njenge-cerebral infarction kanye ne-Myocardial infarction, i-lower endorsement venous thrombosis kanye nezinye izifo. Uma igazi lesiguli lijiya kancane kakhulu, kungenzeka ukuthi libe nokungasebenzi kahle kokujiya kwegazi, livame ukuba nezifo zokopha igazi, njenge-hemophilia, futhi ezimweni ezimbi kakhulu, kuzoshiya ukukhubazeka kwamalunga kanye neminye imiphumela emibi.

Umsebenzi omuhle we-thrombin ubonisa ukuthi ama-platelet asebenza kahle futhi anempilo kakhulu. Ukujiya kwegazi kubhekisela enkambisweni yokushintsha kwegazi kusuka esimweni sokugeleza kuya esimweni sejeli, futhi umongo walo inqubo yokuguqula i-fibrinogen encibilikayo ibe yi-fibrinogen engancibiliki ku-plasma. Ngomqondo omncane, lapho imithambo yegazi yonakele, umzimba ukhiqiza izinto ezijiya igazi, ezivuselelwa ukuze zikhiqize i-thrombin, ekugcineni eguqula i-fibrinogen ibe yi-fibrin, ngaleyo ndlela ikhuthaze ukujiya kwegazi. Ukujiya kwegazi ngokuvamile kuhlanganisa nomsebenzi we-platelet.

Ukunquma ukuthi ukujiya kwe-coagulation kuhle noma cha kungenxa yokuhlolwa kwegazi kanye nokuhlolwa kwelebhu. Ukungasebenzi kahle kokujiya kwe-coagulation kubhekisela ezinkingeni zezinto ezijiya, ukwehla kwenani noma ukusebenza okungajwayelekile, kanye nochungechunge lwezimpawu zokuphuma kwegazi. Ukopha okungahleliwe kungenzeka, futhi i-purpura, i-ecchymosis, i-epistaxis, izinsini eziphuma igazi, kanye ne-hematuria kungabonakala esikhumbeni kanye nasezingxeni zama-mucous. Ngemva kokulimala noma ukuhlinzwa, inani lokopha liyakhula futhi isikhathi sokopha singandiswa. Ngokuthola isikhathi se-prothrombin, isikhathi se-prothrombin esisebenza kancane kanye nezinye izinto, kutholakala ukuthi umsebenzi wokujiya kwe-coagulation awulungile, futhi imbangela yokuxilongwa kufanele icaciswe.