Ixesha le-Thrombin (TT) kunye nexesha le-prothrombin (PT) lisetyenziswa ngokuqhelekileyo izibonakaliso zokufumanisa umsebenzi we-coagulation, umahluko phakathi kwezi zibini zilele ekuboneni izinto ezahlukeneyo zokudibanisa.

Ixesha le-Thrombin (TT) lisalathiso sexesha elifunekayo ukufumanisa ukuguqulwa kwe-plasma prothrombin kwi-thrombin.Isetyenziselwa ikakhulu ukuvavanya imeko yomsebenzi we-fibrinogen kunye ne-coagulation factor I, II, V, VIII, X kunye ne-XIII kwiplasma.Ngethuba lenkqubo yokufumanisa, inani elithile le-tissue prothrombin kunye ne-calcium ions yongezwa ukuguqula i-prothrombin kwi-plasma ibe yi-thrombin, kwaye ixesha lokuguqulwa lilinganiswa, elixabiso le-TT.

Ixesha leProthrombin (PT) lisalathiso sokubona umsebenzi wezinto zokudibanisa igazi ngaphandle kwenkqubo ye-coagulation yegazi.Ngethuba lenkqubo yokufumanisa, inani elithile le-coagulation factor composition (ezifana ne-coagulation factor II, V, VII, X kunye ne-fibrinogen) yongezwa ukuze kusebenze inkqubo ye-coagulation, kwaye ixesha lokubunjwa kwe-clot lilinganiswa, elixabiso le-PT.Ixabiso le-PT libonisa ubume bomsebenzi we-coagulation factor ngaphandle kwe-coagulation system.

Kufuneka kuqatshelwe ukuba iimpawu ze-TT kunye ne-PT zisetyenziswa ngokuqhelekileyo izikhombisi zokulinganisa umsebenzi we-coagulation, kodwa ezimbini azikwazi ukuthatha indawo enye kwenye, kwaye izikhombisi ezifanelekileyo zokubona kufuneka zikhethwe ngokwemeko ethile.Ngexesha elifanayo, kufuneka kuqatshelwe ukuba ukungafani kweendlela zokufumanisa kunye ne-reagents kunokuchaphazela ukuchaneka kweziphumo, kwaye ingqalelo kufuneka ihlawulwe kwimisebenzi esemgangathweni kwimisebenzi yeklinikhi.