Nako ea Thrombin (TT) le nako ea prothrombin (PT) hangata li sebelisoa e le matšoao a ho lemoha mosebetsi oa coagulation, phapang lipakeng tsa tse peli e ho lemoheng lintlha tse fapaneng tsa coagulation.

Nako ea Thrombin (TT) ke sesupo sa nako e hlokahalang ho lemoha phetoho ea prothrombin ea plasma hore e be thrombin. E sebelisoa haholo-holo ho lekola boemo ba ts'ebetso ea fibrinogen le likarolo tsa coagulation I, II, V, VIII, X le XIII plasma. Nakong ea ts'ebetso ea ho lemoha, palo e itseng ea li-ion tsa prothrombin le calcium tsa lisele lia eketsoa ho fetolela prothrombin plasma hore e be thrombin, 'me nako ea phetoho ea lekanyetsoa, ​​​​e leng boleng ba TT.

Nako ea prothrombin (PT) ke index ea ho lemoha ts'ebetso ea lintho tse kopanyang mali ka ntle ho sistimi ea ho kopanya mali. Nakong ea ts'ebetso ea ho lemoha, ho eketsoa palo e itseng ea motsoako oa lintho tse kopanyang mali (joalo ka lintho tse kopanyang mali II, V, VII, X le fibrinogen) ho kenya tšebetsong sistimi ea ho kopanya mali, 'me nako ea ho thehoa ha maqeba e lekanngoa, e leng boleng ba PT. Boleng ba PT bo bonts'a boemo ba ts'ebetso ea lintho tse kopanyang mali ka ntle ho sistimi ea ho kopanya mali.

Ho lokela ho hlokomeloa hore boleng ba TT le PT ka bobeli ke matšoao a sebelisoang hangata ho lekanya ts'ebetso ea ho kopana ha mali, empa tse peli li ke ke tsa nkela tse ling sebaka, 'me matšoao a nepahetseng a ho lemoha a lokela ho khethoa ho latela boemo bo itseng. Ka nako e ts'oanang, ho lokela ho hlokomeloa hore phapang ea mekhoa ea ho lemoha le li-reagent e ka ama ho nepahala ha liphetho, 'me tlhokomelo e lokela ho lefshoa lits'ebetsong tse tloaelehileng ts'ebetsong ea bongaka.