Nthawi ya Thrombin (TT) ndi nthawi ya prothrombin (PT) nthawi zambiri zimagwiritsidwa ntchito pozindikira ntchito ya coagulation, kusiyana pakati pa ziwirizi kuli pakuzindikira zinthu zosiyanasiyana zozungulira.

Nthawi ya Thrombin (TT) ndi chizindikiro cha nthawi yomwe ikufunika kuti munthu adziwe kusintha kwa prothrombin ya plasma kukhala thrombin. Imagwiritsidwa ntchito makamaka poyesa momwe fibrinogen ndi coagulation factors I, II, V, VIII, X ndi XIII zimagwirira ntchito mu plasma. Panthawi yozindikira, kuchuluka kwa ma prothrombin ndi calcium ions kumawonjezedwa kuti asinthe prothrombin mu plasma kukhala thrombin, ndipo nthawi yosinthira imayesedwa, yomwe ndi TT value.

Nthawi ya prothrombin (PT) ndi chizindikiro chodziwira momwe magazi amagwirira ntchito kunja kwa dongosolo lozungulira magazi. Panthawi yozindikira, kuchuluka kwa zinthu zozungulira magazi (monga zinthu zozungulira II, V, VII, X ndi fibrinogen) kumawonjezedwa kuti kuyambitse dongosolo lozungulira magazi, ndipo nthawi yopangira magazi imayesedwa, yomwe ndi mtengo wa PT. Mtengo wa PT umasonyeza momwe magazi amagwirira ntchito kunja kwa dongosolo lozungulira magazi.

Tiyenera kudziwa kuti ma TT ndi ma PT onse ndi zizindikiro zomwe zimagwiritsidwa ntchito kwambiri poyesa ntchito yotseka magazi, koma ziwirizi sizingalowe m'malo, ndipo zizindikiro zoyenera zodziwira ziyenera kusankhidwa malinga ndi vuto lenilenilo. Nthawi yomweyo, tiyenera kudziwa kuti kusiyana kwa njira zodziwira ndi ma reagents kungakhudze kulondola kwa zotsatira, ndipo chisamaliro chiyenera kuperekedwa ku ntchito zokhazikika m'machitidwe azachipatala.