Kutseka kwa magazi nthawi zambiri sikupezeka kaya ndi kwabwino kapena koipa. Kutseka kwa magazi kumakhala ndi nthawi yokhazikika. Ngati kuli kofulumira kwambiri kapena pang'onopang'ono, kungakhale kovulaza thupi la munthu.

Kugayika kwa magazi kumakhala mkati mwa mulingo winawake wabwinobwino, kuti asayambitse kutuluka magazi ndi kupangika kwa magazi m'thupi la munthu. Ngati kugayika kwa magazi kuli kofulumira kwambiri, nthawi zambiri kumasonyeza kuti thupi la munthu lili mu mkhalidwe wovuta kugayika magazi, ndipo matenda a mtima ndi mitsempha yamagazi amatha kuchitika, monga matenda a ubongo ndi matenda a mtima, matenda a venous thrombosis a m'miyendo ya m'munsi ndi matenda ena. Ngati magazi a wodwalayo agayika pang'onopang'ono kwambiri, mwina amakhala ndi vuto la kugayika magazi, matenda otuluka magazi, monga hemophilia, ndipo pazochitika zazikulu, zimasiya mapindikidwe a mafupa ndi zotsatira zina zoyipa.

Kugwira bwino ntchito kwa magazi m'magazi kumasonyeza kuti ma platelet akugwira ntchito bwino ndipo ndi athanzi kwambiri. Kutsekeka kwa magazi kumatanthauza kusintha kwa magazi kuchoka pakuyenda kupita ku gel, ndipo cholinga chake ndi kusintha fibrinogen yosungunuka kukhala fibrinogen yosasungunuka mu plasma. M'lingaliro lochepa, pamene mitsempha yamagazi yawonongeka, thupi limapanga zinthu zotsekeka, zomwe zimayambitsidwa kuti zipange thrombin, zomwe pamapeto pake zimasintha fibrinogen kukhala fibrin, motero zimapangitsa kuti magazi azitsekeka. Kutsekeka kwa magazi nthawi zambiri kumaphatikizaponso ntchito ya ma platelet.

Kuweruza ngati magazi otsekeka ndi abwino kapena ayi kumachitika makamaka kudzera mu mayeso a magazi ndi labotale. Kulephera kwa magazi otsekeka kumatanthauza mavuto okhudzana ndi zinthu zotsekeka, kuchepa kwa kuchuluka kapena kusagwira bwino ntchito, komanso zizindikiro zingapo zotuluka magazi. Kutuluka magazi mwadzidzidzi kumatha kuchitika, ndipo purpura, ecchymosis, epistaxis, mkamwa wotuluka magazi, ndi hematuria zimatha kuwoneka pakhungu ndi mucous membranes. Pambuyo pa kuvulala kapena opaleshoni, kuchuluka kwa magazi kumawonjezeka ndipo nthawi yotuluka magazi imatha kukulitsidwa. Kudzera mu kuzindikira nthawi ya prothrombin, nthawi ya prothrombin yomwe yayamba kugwira ntchito pang'ono ndi zinthu zina, zimapezeka kuti ntchito yotsekeka si yabwino, ndipo chifukwa cha matendawa chiyenera kufotokozedwa bwino.