What is the function of thrombin?


Author: Succeeder    

Thrombin is a kind of white to gray -white non -crystalline substance, generally frozen -dried powder. THROMBIN is a kind of white to gray -white non -crystalline substance, generally frozen -dried powder.

Thrombin is also called coagulation factor Ⅱ, which is a multifunctional coagulation factor. The main function is to decompose fibrin original, make each fibrin primary tetrachide take off four sections of small peptides, and the remaining part is a fiber protein monomer. These monomers are intertwined to form a loose mesh, which is soluble. Under the action of coagulation factor ions and calcium ions, fibrin monomers aggregate each other to form an insoluble cross -linked fibrin polymer clot.

Thrombin is the most important coagulation factor in the process of human coagulation. The main function is to activate the fibrinogen of the human body and make the fibrin original into an active fibrin, which can play a fast coagulation role. At the same time, coagulinase can also negative feedback to accelerate the intrinsic coagulation pathway and the coagulation process of exogenous coagulation pathway, which plays an important role in the coagulation process of the human body. In addition, coordinase is also a commonly used name of hemostatic drugs commonly used in clinical practice. It is mainly suitable for diseases such as digestive system bleeding, surgical bleeding, gynecological bleeding. It has strict indications and needs to be applied under the guidance of doctors.

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