ʻO nā hopena maikaʻi ʻole i hoʻokumu ʻia e ka hana coagulation maʻamau ʻole e pili pono ana i ke ʻano o ka coagulation maʻamau ʻole, a ʻo ka loiloi kikoʻī penei:

1. Kūlana Hypercoagulable: Inā loaʻa i ka mea maʻi kahi kūlana hypercoagulable, hiki i kēlā kūlana hypercoagulable ma muli o ke koko coagulable maʻamau ke hana i kahi moʻo o nā hopena. No ka laʻana, ʻo nā mea maʻi i kahi kūlana hypercoagulable e maʻalahi i ka thrombosis, a ʻo ka embolism e maʻalahi ke hana ma hope o ka thrombosis. Inā hana ka embolism i loko o ka ʻōnaehana nerve waena, ʻo ka infarction cerebral, hemiplegia, aphasia a me nā hōʻike ʻē aʻe e hana pinepine ʻia. Inā hana ka embolism i loko o nā māmā, e alakaʻi ana i ka embolism pulmonary i nā mea maʻi me ka hypercoagulability, ʻaʻole hiki ke hoʻomaikaʻi ʻia nā hōʻailona e like me ka wheezing, ka paʻa o ka umauma, a me ka hanu ʻole, ka oxygen koko haʻahaʻa a me ka inhalation oxygen, hiki ke ʻike ʻia ma o nā hoʻokolohua kiʻi e like me ka CT māmā. Hōʻike ʻano Wedge o ka embolism pulmonary. Ke noho ka puʻuwai i kahi kūlana hypercoagulable, hana pinepine ka atherosclerosis coronary cardiovascular. Ma hope o ka hoʻokumu ʻia ʻana o ka thrombus, hoʻomohala pinepine ka mea maʻi i ka maʻi coronary syndrome acute, me nā hōʻailona e like me ka myocardial infarction a me ka angina pectoris. Hiki i ka embolism ma nā ʻāpana ʻē aʻe o nā ʻaoʻao haʻahaʻa ke hana i ka edema asymmetrical o nā ʻaoʻao haʻahaʻa. Inā loaʻa ia i loko o ke ala ʻōpū, loaʻa pinepine ka thrombosis mesenteric, a hiki ke loaʻa nā hopena ʻino e like me ka ʻeha o ka ʻōpū a me ka ascites;

2. Kūlana Hypocoagulable: Ma muli o ka nele o nā mea coagulation i loko o ke kino o ka mea maʻi a i ʻole ke kāohi ʻana o ka hana coagulation, ʻike pinepine ʻia ke ʻano o ke kahe koko, e like me ke kahe ʻana o nā ʻāʻī, epistaxis (ke kahe ʻana o ke koko ihu a me nā ecchymoses nui ma ka ʻili), a i ʻole ka hemahema nui o ka mea coagulation, e like me ka hemophilia. Loaʻa i ka mea maʻi ke kahe koko o ke koko o ka hui, a ʻo ke kahe koko o ka lua hui pinepine e alakaʻi ai i ka deformity o nā hui, kahi e hoʻopilikia ai i ke ola maʻamau. I nā hihia koʻikoʻi, hiki ke loaʻa ke kahe koko o ka lolo, kahi e hoʻoweliweli ai i ke ola o ka mea maʻi.