Thrombin na iya haɓaka coagulation na jini, yana taka rawa wajen dakatar da zubar jini, kuma yana iya haɓaka warkar da raunuka da gyaran kyallen takarda.

Thrombin wani muhimmin sinadari ne na enzyme a cikin tsarin hada jini, kuma muhimmin enzyme ne wanda aka fara canza shi zuwa fibrin a cikin fibrin. Lokacin da jijiyoyin jini suka lalace, ana samar da glycrase a ƙarƙashin aikin platelets da ƙwayoyin endothelial na jijiyoyin jini, wanda ke haɓaka haɗakar platelets da thrombosis, ta haka ne ke dakatar da hemostasis. Bugu da ƙari, coordinase kuma yana iya haɓaka warkar da rauni da gyaran nama, wanda shine sinadari mai mahimmanci na enzyme a cikin gyaran nama.

Ya kamata a lura cewa yawan kunna thrombin na iya haifar da matsaloli kamar thrombosis da cututtukan zuciya da jijiyoyin jini. Saboda haka, ya zama dole a bi shawarar likita da kuma yawan magungunan da ake amfani da su yayin amfani da magungunan da suka shafi coordinase don guje wa mummunan sakamako da illa.

Aikin fibrinogen a farko shine tasirin haɓaka haɗakar platelets a cikin haɗakar jini. Fibrinogen a asali muhimmin furotin ne a cikin tsarin haɗakar jini. Babban aikinsa shine haɗakar jini da hemostasis, da kuma shiga cikin samar da platelets. Matsakaicin ƙimar fibrinogen shine 2-4g/L. Haɓaka matakin fibrinogen na asali yana da alaƙa da faruwar cututtukan thrombosis. Haɓakar haɓakar fibrin na iya faruwa ne sakamakon abubuwan da suka shafi ilimin halittar jiki, kamar lokacin daukar ciki da shekaru, ko abubuwan da suka shafi cututtuka, kamar hawan jini, ciwon suga, cututtukan zuciya na atherosclerotic.

Yawan fibrin yana raguwa, wanda cututtukan hanta, kamar cirrhosis da hepatitis mai tsanani, na iya haifar da shi. Marasa lafiya suna buƙatar zuwa asibiti don a duba su a kan lokaci kuma a yi musu magani a ƙarƙashin jagorancin likita.