I-Thrombosis ngokuvamile ibangelwa ukulimala kwamaseli endothelial enhliziyo nemithambo yegazi, isimo sokugeleza kwegazi okungajwayelekile, kanye nokwanda kokujiya kwegazi.

1. Ukulimala kweseli le-endothelial yenhliziyo nemithambo yegazi: Ukulimala kweseli le-endothelial yemithambo yegazi kuyimbangela ebaluleke kakhulu nevame kakhulu yokwakheka kwe-thrombus, okuyinto evame kakhulu kwi-rheumatic and infective endocarditis, i-atherosclerotic plaque ulcer enzima, ukunyakaza okubuhlungu noma okuvuvukalayo Indawo yokulimala kwemithambo yegazi, njll. Ngaphezu kwalokho, ngemva kokuntuleka kwe-hypoxia, ukushaqeka, i-sepsis kanye ne-bacterial endotoxin kubangela umonakalo omkhulu we-endothelial emzimbeni wonke, i-collagen ngaphansi kwe-endothelium ivuselela inqubo yokujiya kwegazi, okuholela ekujiya kwegazi okusabalele ngaphakathi kwemithambo yegazi, kanye nokwakheka kwe-thrombus ku-microcirculation yomzimba wonke.

2. Isimo esingavamile sokugeleza kwegazi: ikakhulukazi sibhekisela ekunciphiseni ukugeleza kwegazi kanye nokukhiqizwa kwama-eddies ekugelezeni kwegazi, njll. Izinto ezisebenza ngokujiya kanye ne-thrombin zifinyelela izinga elidingekayo ukuze kujiyane endaweni yasendaweni, okusiza ekwakhekeni kwe-thrombus. Phakathi kwazo, imithambo ithambekele kakhulu ekujiyani, okuyinto evame kakhulu ezigulini ezinesifo senhliziyo, izifo ezingamahlalakhona kanye nokuphumula kombhede ngemva kokuhlinzwa. Ngaphezu kwalokho, ukugeleza kwegazi enhliziyweni nasemithanjeni kuyashesha, futhi akulula ukwakha i-thrombus. Kodwa-ke, lapho ukugeleza kwegazi ku-atrium yangakwesobunxele, i-aneurysm, noma igatsha lomthambo wegazi kuhamba kancane futhi kwenzeka i-eddy current ngesikhathi se-mitral valve stenosis, nayo ithambekele ekujiyani.

3. Ukwanda kokujiya kwegazi: Ngokuvamile, ukwanda kwama-platelet kanye nezici zokujiya kwegazi, noma ukwehla komsebenzi wohlelo lwe-fibrinolytic, kuholela esimweni sokujiya kwegazi ngokweqile, esivame kakhulu ezimweni ze-hypercoagulable ezizuzwe njengefa nezitholwe.

Ngaphezu kwalokho, ukubuya kwegazi okungekuhle emithanjeni nakho kungabangela lokhu. Ngokusho kokuxilongwa okuphumelelayo kwesifo sakho, ukuvimbela nokwelashwa okuqondisiwe kwesayensi kungafinyelelwa ukusiza ekululameni kwempilo.