Umzimba ojwayelekile unesistimu ephelele yokujiya kanye neyokuvimbela ukujiya kwegazi. Uhlelo lokujiya kanye nesistimu yokuviya igazi zigcina ibhalansi eguquguqukayo ukuqinisekisa ukuthi i-hemostasis yomzimba kanye nokugeleza kwegazi okubushelelezi. Uma ibhalansi yokusebenza kokujiya kanye neyokuvimbela ukujiya kwegazi isiphazamisekile, kuzoholela ekuthambekeleni kokopha kanye ne-thrombosis.

1. Umsebenzi wokuqina komzimba

Uhlelo lokujiya lwakhiwe kakhulu yizinto ezijiyayo. Izinto ezihileleke ngqo ekujiya zibizwa ngokuthi izinto ezijiyayo. Kunezici eziyi-13 eziqashelwayo zokujiya.

Kunezindlela zokuvuselela izicubu zomzimba kanye nezindlela zokuvuselela izicubu zomzimba zangaphandle ukuze kusebenze izici zokugaya ukudla.

Okwamanje kukholelwa ukuthi ukusebenza kohlelo lokujiya kwangaphandle oluqalwa yi-tissue factor kudlala indima enkulu ekuqalisweni kokujiya. Ukuxhumana okuseduze phakathi kwezinhlelo zokujiya kwangaphakathi nangaphandle kudlala indima ebalulekile ekuqaliseni nasekulondolozeni inqubo yokujiya.

2. Umsebenzi womzimba wokuvimbela ukujiya kwegazi

Uhlelo lokuvimbela ukujiya kwegazi luhlanganisa uhlelo lokuvimbela ukujiya kwegazi kwamaseli kanye nohlelo lokuvimbela ukujiya kwegazi lomzimba.

①Isistimu yokuvimbela ukujiya kwamaseli

Kubhekisele ku-phagocytosis ye-coagulation factor, i-tissue factor, i-prothrombin complex kanye ne-soluble fibrin monomer yi-mononuclear-phagocyte system.

②Isistimu yokuvimbela ukujiya koketshezi lomzimba

Kufaka phakathi: ama-serine protease inhibitors, ama-protein C-based protease inhibitors kanye nama-tissue factor pathway inhibitors (TFPI).

3. Uhlelo lwe-Fibrinolytic kanye nemisebenzi yalo

Ikakhulukazi zifaka phakathi i-plasminogen, i-plasmin, i-plasminogen activator kanye ne-fibrinolysis inhibitor.

Indima yesistimu ye-fibrinolytic: ukuncibilikisa amahlule e-fibrin nokuqinisekisa ukujikeleza kwegazi okubushelelezi; ukubamba iqhaza ekulungisweni kwezicubu kanye nokuvuselelwa kwemithambo yegazi.

4. Indima yamaseli endothelial emithambo yegazi enqubweni yokujiya, ukuvimbela ukujiya kwegazi kanye ne-fibrinolysis

① Khiqiza izinto ezahlukahlukene ezisebenzayo ngokwezinto eziphilayo;

②Lawula ukujiya kwegazi kanye nomsebenzi wokulwa nokujiya kwegazi;

③Lungisa umsebenzi wohlelo lwe-fibrinolysis;

④ Lawula ukucindezeleka kwemithambo yegazi;

⑤Bamba iqhaza ekuxazululeni ukuvuvukala;

⑥ Gcina umsebenzi we-microcirculation, njll.

Izinkinga zokuqina kwegazi kanye ne-anticoagulant

1. Ukungahambi kahle kwezinto ezibangela ukujiya kwegazi.

2. Ukungajwayelekile kwezinto ezilwa nokuvuvukala kwemithambo yegazi ku-plasma.

3. Ukungajwayelekile kwe-fibrinolytic factor ku-plasma.

4. Ukukhubazeka kwamaseli egazi.

5. Imithambo yegazi engajwayelekile.