I-TT ibhekisa kwixesha lokujiya kwegazi emva kokongeza i-thrombin eqhelekileyo kwi-plasma. Kwindlela eqhelekileyo yokujiya, i-thrombin evelisiweyo iguqula i-fibrinogen ibe yi-fibrin, enokubonakaliswa yi-TT. Ngenxa yokuba iimveliso zokujiya kwe-fibrin (proto) (FDP) zinokwandisa i-TT, abanye abantu basebenzisa i-TT njengovavanyo lokuhlola inkqubo ye-fibrinolytic.
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