Izifo zokopha zibhekisa kwizifo ezibonakaliswa kukopha okuzenzekelayo okanye okuncinci emva kokwenzakala ngenxa yezinto zemfuza, zokuzalwa, kunye nezinto ezifunyenweyo ezibangela iziphene okanye ukungaqheleki kwindlela yokuhambisa igazi efana nemithambo yegazi, iiplatelets, i-anticoagulation, kunye ne-fibrinolysis. Kukho izifo ezininzi zokopha egazini kwiklinikhi, kwaye akukho gama lisetyenziswa njengelona liqhelekileyo. Nangona kunjalo, ezixhaphakileyo ziquka i-allergy purpura, i-aplastic anemia, i-dissemed intravascular coagulation, i-leukemia, njl.njl.

1. I-Allergic purpura: Sisifo esibangelwa kukuzikhusela komzimba, ngenxa yezinto ezahlukeneyo ezikhuthazayo, esikhuthaza ukwanda kwee-B cell clones, nto leyo ebangela izilonda kwimithambo yegazi emincinci emzimbeni wonke, nto leyo ekhokelela ekuphumeni kwegazi, okanye sinokuhamba neempawu ezifana nentlungu yesisu, ukuhlanza, kunye nokudumba kunye nentlungu yamalungu;

2. I-Aplastic anemia: Ngenxa yokuvuselelwa ngamayeza, imitha yomzimba, kunye nezinye izinto, iziphene kwiiseli ze-hematopoietic stem ziyenzeka, ezichaphazela ukusebenza komzimba kunye nokusingqongileyo kwe-hematopoiesis, azikhuthazi ukwanda kunye nokwahlukana kweeseli ze-hematopoietic, zinokubangela ukopha, kwaye zihamba kunye neempawu ezifana nosulelo, umkhuhlane, kunye ne-anemia eqhubekayo;

3. Ukuxinana kwemithambo yegazi okusasazekayo: kunokubangelwa ziimpawu ezahlukeneyo, okuvuselela inkqubo yokuxinana kwemithambo yegazi. Kwinqanaba lokuqala, i-fibrin kunye neeplatelets ziqokelelana kwi-microvasculature kwaye zenze amahlwili egazi. Njengoko imeko iqhubeka, izinto zokuxinana kwemithambo yegazi kunye neeplatelets zisetyenziswa kakhulu, zivuselela inkqubo ye-fibrinolytic, nto leyo ekhokelela ekopheni okanye ekuhambeni neempawu ezifana nokuphazamiseka kokujikeleza kwegazi, ukungasebenzi kakuhle kwamalungu omzimba, kunye nomothuko;

4. I-Leukemia: Umzekelo, kwi-acute leukemia, isigulana siba ne-thrombocytopenia kwaye inani elikhulu leeseli ze-leukemia lenza i-leukemia thrombi, nto leyo ebangela ukuba imithambo yegazi iqhekeke ngenxa yokucinezelwa, nto leyo ekhokelela ekuphumeni kwegazi, kwaye inokukhatshwa yi-anemia, umkhuhlane, ukwanda kwe-lymph node, kunye nezinye iimeko.

Ukongeza, i-myeloma kunye ne-lymphoma nazo zinokubangela ukungasebenzi kakuhle kokuqina kwegazi, okubangela ukopha. Uninzi lwezigulane ezinezifo zokopha ziya kufumana ukopha okungaqhelekanga eluswini nakwi-submucosa, kunye nemivumbo emikhulu eluswini. Amatyala amakhulu okopha igazi anokubonakala kunye neempawu ezifana nokudinwa, ubuso obukhanyayo, imilebe, kunye neebhedi zezipikili, kunye neempawu ezifana nesiyezi, ukozela, kunye nokungaqondi kakuhle. Iimpawu ezincinci kufuneka ziphathwe ngamayeza okuhambisa igazi. Ukopha igazi okukhulu, i-plasma entsha okanye igazi eliyinxenye linokufakwa njengoko kuyimfuneko ukongeza iiplatelets kunye nezinto zokopha emzimbeni.