I-Thrombin luhlobo lwento emhlophe ukuya kwengwevu-mhlophe engeyiyo ikristale, ngokubanzi ingumgubo owomileyo oqandisiweyo. I-THROMBIN luhlobo lwento emhlophe ukuya kwengwevu-mhlophe engeyiyo ikristale, ngokubanzi ingumgubo owomileyo oqandisiweyo.

I-Thrombin ikwabizwa ngokuba yi-coagulation factor Ⅱ, eyi-multifunctional coagulation factor. Umsebenzi ophambili kukubola i-fibrin yokuqala, ukwenza i-tetrachide nganye ye-fibrin primary ikhuphe amacandelo amane ee-peptides ezincinci, kwaye inxalenye eseleyo yi-fiber protein monomer. Ezi monomers zidibene ukwenza i-loose mesh, enyibilikayo. Phantsi kwesenzo se-coagulation factor ions kunye ne-calcium ions, ii-fibrin monomers ziyahlangana ukuze zenze i-clot ye-fibrin polymer edibeneyo enganyibilikiyo.

I-Thrombin yeyona nto ibalulekileyo ekujikeni kwemithambo yegazi kwinkqubo yokujiya komzimba womntu. Umsebenzi ophambili kukuvula i-fibrinogen yomzimba womntu nokwenza i-fibrin yokuqala ibe yi-fibrin esebenzayo, enokudlala indima yokujiya ngokukhawuleza. Kwangaxeshanye, i-coagulinase inokuba nempendulo engalunganga yokukhawulezisa indlela yokujiya komzimba kunye nenkqubo yokujiya kwendlela yokujiya yangaphandle, edlala indima ebalulekileyo kwinkqubo yokujiya komzimba womntu. Ukongeza, i-coordinase ikwaligama elisetyenziswa rhoqo lamayeza e-hemostatic asetyenziswa rhoqo kwizonyango. Ifanelekile kakhulu kwizifo ezinje ukopha kwenkqubo yokugaya ukutya, ukopha ngotyando, ukopha kwabasetyhini. Ineempawu ezingqongqo kwaye kufuneka isetyenziswe phantsi kwesikhokelo soogqirha.