I-Thrombosis idla ngokubangelwa kukonakala kweeseli ze-endothelial zentliziyo, imeko engaqhelekanga yokuhamba kwegazi, kunye nokwanda kokujiya kwegazi.

1. Ukulimala kweseli ye-endothelial yentliziyo: Ukulimala kweseli ye-endothelial yemithambo yegazi yeyona nto ibalulekileyo neqhelekileyo yokwakheka kwe-thrombus, exhaphake kakhulu kwi-rheumatic kunye ne-infective endocarditis, i-atherosclerotic plaque ulcer enzima, intshukumo ebuhlungu okanye yokudumba Indawo yokwenzakala kwemithambo, njl. Ukongeza, emva kokungabikho koxinzelelo lwegazi, ukushaqeka, i-sepsis kunye ne-bacterial endotoxin zibangela umonakalo omkhulu we-endothelial emzimbeni wonke, i-collagen phantsi kwe-endothelium ivuselela inkqubo yokujiya kwegazi, okubangela ukujiya kwegazi ngaphakathi kwemithambo, kwaye i-thrombus iyenzeka kwi-microcirculation yomzimba wonke.

2. Imeko engaqhelekanga yokuhamba kwegazi: ikakhulu ibhekisa ekunciphiseni ukuhamba kwegazi kunye nokuveliswa kwee-eddies ekuhambeni kwegazi, njl. Izinto ezisebenza ngokuxinana kwegazi kunye ne-thrombin zifikelela kuxinzelelo olufunekayo ukuze kuxinane kwindawo yasekuhlaleni, nto leyo enceda ekwakhekeni kwe-thrombus. Phakathi kwazo, imithambo ichaphazeleka kakhulu yi-thrombus, nto leyo exhaphake kakhulu kwizigulana ezinesifo sentliziyo, izifo ezingapheliyo kunye nokuphumla ebhedini emva kotyando. Ukongeza, ukuhamba kwegazi entliziyweni nakwimithambo yegazi kuyakhawuleza, kwaye akulula ukwenza i-thrombus. Nangona kunjalo, xa ukuhamba kwegazi kwi-atrium yasekhohlo, i-aneurysm, okanye isebe lomthambo wegazi licotha kwaye i-eddy current yenzeka ngexesha le-mitral valve stenosis, ikwachaphazeleka yi-thrombosis.

3. Ukwanda kokujiya kwegazi: Ngokubanzi, ukwanda kweeplatelets kunye nezinto ezijiya egazini, okanye ukwehla komsebenzi wenkqubo ye-fibrinolytic, kukhokelela kwimeko yokujiya kwegazi, exhaphake kakhulu kwiimeko ze-hypercoagulable zelifa kunye nezo zifunyenweyo.

Ukongeza, ukubuya kwegazi okungekuhle kwimithambo yegazi nako kunokubangela oku. Ngokwendlela umntu axilongwa ngayo isifo sakhe, uthintelo lwesayensi olujoliswe kuyo kunye nonyango lunokufezekiswa ukunceda ekubuyiseleni impilo yakhe esichengeni.