I-FIB sisifinyezo sesiNgesi se-fibrinogen, kwaye i-fibrinogen yinto ebangela ukujiya kwegazi. Ujiya wegazi ophezulu Ixabiso le-FIB lithetha ukuba igazi likwimeko yokujiya kwegazi kakhulu, kwaye i-thrombus yakheka lula.

Emva kokuba indlela yokujiya kwegazi yomntu isebenze, i-fibrinogen iba yi-fibrin monomer phantsi kwesenzo se-thrombin, kwaye i-fibrin monomer inokudibana ibe yi-fibrin polymer, eluncedo ekwakhiweni kwe-blood clot kwaye idlala indima ebalulekileyo kwinkqubo yokujiya kwegazi.

I-Fibrinogen yenziwa ikakhulu zii-hepatocytes kwaye yiproteni enomsebenzi wokujiya. Ixabiso layo eliqhelekileyo liphakathi kwe-2 ~ 4qL. I-Fibrinogen yinto enxulumene nokujiya, kwaye ukwanda kwayo kudla ngokuba yimpendulo engaqhelekanga yomzimba kwaye yimbangela yezifo ezinxulumene ne-thromboembolism.
Ixabiso le-FIB lokuxinana linokunyuswa kwizifo ezininzi, izinto eziqhelekileyo zemfuza okanye zokudumba, ii-lipids eziphezulu zegazi, uxinzelelo lwegazi

Isifo sentliziyo esiphakamileyo, isifo seswekile, isifo sephepha, isifo sezicwili ezidityanisiweyo, isifo sentliziyo, kunye neethumba ezinobungozi. Xa uphethwe zizo zonke ezi zifo zingasentla kunokukhokelela ekubeni kubekho amahlwili egazi. Ke ngoko, ukujiya kwegazi okuphezulu Ixabiso le-FIB libhekisa kwimeko yokujiya kwegazi okuphezulu.