ʻO FIB ka ʻōlelo Pelekane no ka fibrinogen, a ʻo ka fibrinogen kahi mea hoʻohui.ʻO ka waiwai FIB coagulation koko kiʻekiʻe, ʻo ia ka mea aia ke koko i kahi kūlana hypercoagulable, a ua maʻalahi ka thrombus.

Ma hope o ka hana ʻana o ke ʻano coagulation kanaka, lilo ka fibrinogen i ka monomer fibrin ma lalo o ka hana o ka thrombin, a hiki i ka monomer fibrin ke hōʻuluʻulu i ka polymer fibrin, he mea kōkua ia no ka hoʻokumu ʻana i ke koko a he mea nui i ka hana coagulation.

Hoʻopili nui ʻia ka Fibrinogen e nā hepatocytes a he protein me ka hana coagulation.Aia kona waiwai maʻamau ma waena o 2~4qL.ʻO ka Fibrinogen kahi mea e pili ana i ka coagulation, a ʻo kona hoʻonui pinepine ʻana he hopena ʻaʻole kikoʻī o ke kino a he mea pilikia ia no nā maʻi pili thromboembolism.
Hiki ke hoʻonui ʻia ka waiwai o ka coagulation FIB i nā maʻi he nui, nā genetic maʻamau a i ʻole nā ​​​​mea inflammatory, nā lipid koko kiʻekiʻe, ke koko koko.

ʻO ka maʻi kiʻekiʻe, ka maʻi maʻi puʻuwai, ka maʻi diabetes, ka maʻi maʻi, ka maʻi pili, ka maʻi puʻuwai, a me nā maʻi maʻi ʻino.i ka loaʻa ʻana o nā maʻi āpau i luna aʻe e hiki ke alakaʻi i ke ʻano o ke koko koko.No laila, ʻo ka waiwai FIB coagulation koko kiʻekiʻe e pili ana i kahi kūlana o ka coagulation koko kiʻekiʻe.