I-APTT sisifinyezo sesiNgesi sexesha le-prothrombin elisebenza kancinci. I-APTT luvavanyo lokuhlola olubonisa indlela yokujiya kwegazi engapheliyo. I-APTT ende ibonisa ukuba into ethile yokujiya kwegazi ebandakanyeka kwindlela yokujiya kwegazi engapheliyo yomntu ayisebenzi kakuhle. Emva kokuba i-APTT ithathe ixesha elide, isigulana siya kuba neempawu ezicacileyo zokopha. Umzekelo, izigulana ezine-hemophilia A, i-hemophilia B, kunye nesifo se-von Willebrand zonke ziya kuba ne-APTT ende, kwaye isigulana siya kuba ne-ecchymosis eluswini nakwii-membranes ze-mucous, kunye nokopha kwemisipha. , ukopha kwamalungu, i-hematoma, njl. Ingakumbi kwizigulana ezine-hemophilia A, ukukhubazeka kwamalungu kunye nokuwohloka kwemisipha kuhlala kushiyeka emva kokuba i-hematoma ifunxwe ngenxa ye-synovitis ebangelwa kukopha kwamalungu, okunempembelelo enkulu kwimpilo. Ukongeza, ukujiya kwegazi okusasazeka ngaphakathi kwemithambo yegazi, isifo sesibindi esiqatha kunye nezinye izifo nazo ziya kubangela ukolulwa okukhulu kwe-APTT, okuya kubangela umonakalo ocacileyo emzimbeni womntu.
Ixabiso eliphezulu le-Aptt libonisa ukuba isigulana sinokuba neengxaki zokopha. Iingxaki zokopha eziqhelekileyo ziquka ukungabikho kwe-congenital coagulation factor kunye ne-hemophilia. Okwesibini, kurhanelwa ukuba ibangelwa sisifo sesibindi okanye i-obstructive jaundice okanye isifo se-thrombotic. Akukacaci nokuba ibangelwa yimpembelelo yezinto ezisetyenziswa ngamayeza, njengokusetyenziswa ixesha elide kwamayeza okulwa nokugabha igazi. Ngokwezonyango, uvavanyo lwe-aptt lunokusetyenziswa ukugweba ukuba umsebenzi wokugabha igazi emzimbeni wesigulana uqhelekile na. Ukuba kungenxa yento ebangelwa yi-hemophilia, kuyacetyiswa ukuba ulandele icebiso likagqirha lokuyeka ukopha okanye usebenzise unyango lwe-prothrombin complex.