Ukubeka esweni okunamandla kwe-D-Dimer kuqikelela ukwakheka kwe-VTE:
Njengoko bekutshiwo ngaphambili, isiqingatha sobomi be-D-Dimer ziiyure ezisi-7-8, nto leyo ebangelwa yile mpawu yokuba i-D-Dimer ikwazi ukujonga ngokuguquguqukayo kwaye iqikelele ukwakheka kwe-VTE. Kwi-hypercoagulability yexeshana okanye ukwakheka kwe-microthrombosis, i-D-Dimer iya kwanda kancinci ize inciphe ngokukhawuleza. Xa kukho ukwakheka kwe-clot yegazi entsha eqhubekayo emzimbeni, i-D-Dimer emzimbeni iya kuqhubeka inyuka, iveze i-peak like elevation curve. Kwizigulane ezine-thrombosis ephezulu, njengeemeko ezibukhali nezinzima, izigulane emva kotyando, njl.njl., ukuba kukho ukunyuka okukhawulezileyo kwamanqanaba e-D-Dimer, kuyimfuneko ukuba uqaphele malunga nokuba kungenzeka kwe-thrombosis. Kwi-"Expert Consensus on the Screening and Treatment of Deep Venous Thrombosis in Traumatic Orthopedic Patients", kucetyiswa ukuba kujongwe ngokuguquguqukayo utshintsho kwi-D-Dimer rhoqo emva kweeyure ezingama-48 kwizigulane ezisengozini ephakathi ukuya kweziphezulu emva kotyando lwamathambo. Izigulane ezine-D-Dimer eqhubekayo okanye ephezulu kufuneka zenze uvavanyo lwe-imaging ngexesha elifanelekileyo ukuze zichonge i-DVT.