FIB ke khutsufatso ea Senyesemane bakeng sa fibrinogen, 'me fibrinogen ke ntlha e etsang hore mali a koalehe. Ho koaleha ha mali ho phahameng Boleng ba FIB bo bolela hore mali a boemong ba ho koaleha ha mali haholo, 'me thrombus e thehoa habonolo.
Ka mora hore mokhoa oa ho kopanya mali oa motho o kenngoe tšebetsong, fibrinogen e fetoha fibrin monomer tlas'a ts'ebetso ea thrombin, 'me fibrin monomer e ka kopana ho ba fibrin polymer, e leng se thusang ho thehoeng ha maqeba a mali 'me se bapala karolo ea bohlokoa ts'ebetsong ea ho kopanya mali.
Fibrinogen e hlahisoa haholo-holo ke li-hepatocyte 'me ke protheine e nang le ts'ebetso ea ho hoama. Boleng ba eona bo tloaelehileng bo pakeng tsa 2 ~ 4qL. Fibrinogen ke ntho e amanang le ho hoama, 'me keketseho ea eona hangata ke karabelo e sa tobang ea' mele 'me ke sesosa sa kotsi bakeng sa mafu a amanang le thromboembolism.
Boleng ba FIB ba ho kopana bo ka eketseha mafung a mangata, mabaka a tloaelehileng a lefutso kapa a ho ruruha, mafura a mangata maling, khatello ea mali
Lefu la pelo le phahameng, lefu la pelo, lefu la tsoekere, lefuba, lefu la lisele tse hokahaneng, lefu la pelo, le lihlahala tse kotsi. Ha motho a tšoeroe ke mafu ana kaofela a ka 'na a lebisa ho hlaheng ha makhopho a mali. Ka hona, ho khomarela mali ho phahameng Boleng ba FIB bo bolela boemo ba ho khomarela mali ho phahameng.
Boemo bo phahameng ba fibrinogen bo bolela hore mali a boemong ba ho hohlana ha mali haholo 'me a kotsing ea ho ba le thrombosis. Fibrinogen e boetse e tsejoa e le coagulation factor I. Ebang ke endogenous coagulation kapa e exogenous coagulation, mohato oa ho qetela oa fibrinogen o tla kenya tšebetsong li-fibroblast. Liprotheine li hokahanngoa butle-butle marang-rang ho etsa maqeba a mali, kahoo fibrinogen e emela ts'ebetso ea coagulation ea mali.
Fibrinogen e hlahisoa haholo-holo ke sebete 'me e ka ba teng mafung a mangata. Mabaka a tloaelehileng a liphatsa tsa lefutso kapa a ho ruruha a kenyelletsa mafura a mangata maling, khatello e phahameng ea mali, lefu la pelo, lefu la tsoekere, lefuba, lefu la lisele tse hokahaneng, lefu la pelo, le lihlahala tse kotsi li tla nyoloha. Kamora opereishene e kholo, hobane 'mele o hloka ho etsa mosebetsi oa hemostasis, o tla boela o susumetse keketseho ea fibrinogen bakeng sa mosebetsi oa hemostasis.
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