Coagulation disorder inoisa hupenyu panjodzi, nekuti coagulation kusagadzikana kunokonzerwa nezvikonzero zvakasiyana-siyana izvo zvinoita kuti basa remuviri wemunhu ritadze.Mushure mekuita coagulation dysfunction, muviri wemunhu uchaonekwa nhevedzano yezviratidzo zvekubuda ropa.Kana yakanyanya intracranial hemorrhage ikaitika, inotyisa hupenyu.Nemhaka yokuti coagulation dysfunction inogona kukonzerwa nehosha dzakasiyana-siyana, kuchipatara kunowanzoitika kushayikwa kwevhitamini K, kuparadzira intravascular coagulation, chirwere chakakomba chechiropa, hemophilia a, hemophilia b, von Willebrand chirwere, nezvimwewo.

Kana ari murwere ane hemophilia A yakanyanya, ane katsika kekubuda ropa, uye zviri nyore kupinza kubuda ropa mushure mekukuvadzwa zvishoma.Kana murwere ane hemophilia A akasangana nekukuvadzwa, zviri nyore kuti akonzere kubuda kweropa kwakanyanya muuropi, izvo zvinoisa hupenyu hwemurwere panjodzi.Pamusoro pezvo, yakanyanya kuparadzirwa intravascular coagulation zvakare inokonzeresa kubuda ropa zvakanyanya nekuda kwekushandisa kwakasiyana-siyana coagulation zvinhu uye coagulation dysfunction, zvichikonzera kufa kwekutanga kwevarwere.