E tele ituaiga o fa'ama'i toto, e masani ona fa'avasegaina fa'aklinikal e fa'atatau i le mafua'aga ma le pathogenesis. E mafai ona vaevaeina i ni fa'aletonu o le vascular, platelet, coagulation factor, ma isi.
1. Alatoto:
(1) Tu'ufaasolo: telangiectasia tu'ufaasolo, vascular hemophilia, ma aano lagolago e le masani ai e siomia ai alatoto;
(2) Maua: fa'aleagaina o puipui o alatoto e mafua mai i le allergic purpura, simple purpura, drug-induced purpura, age-related purpura, autoimmune purpura, fa'ama'i pipisi, mea tau metabolism, mea tau vaila'au, mea tau masini, ma isi mea fa'apena.

2. Uiga o le platelet:
(1) Thrombocytopenia: thrombocytopenia puipuia o le tino, thrombocytopenia e mafua mai i fualaau faasaina, anemia aplastic, sosolo o le tumo, leukemia, faamai puipuia o le tino, DIC, splenic hyperfunction, thrombotic thrombocytopenic purpura, ma isi mea faapena;
(2) Thrombocytosis: Thrombocytosis muamua, polycythemia moni, splenectomy, fulafula, fa'aletonu o le platelet inflammatory, thrombocytopenia, giant platelet syndrome, fa'ama'i ate, ma le fa'aletonu o le platelet e mafua mai i le uremia.

3. Mea e le masani ai e mafua ai le toto toto:
(1) Fa'aletonu o le coagulation factor tuufaasolo: hemophilia A, hemophilia B, FXI, FV, FXI, FVII, FVIII, le lava, maualalo (leai) le fibrinogen fananau mai, le lava o le prothrombin, ma le le lava o le complex coagulation factor;
(2) Fa'aletonu o le coagulation factor ua maua: fa'ama'i ate, le lava o le vaitamini K, leukemia fa'afuase'i, lymphoma, fa'ama'i o le connective tissue, ma isi mea fa'apena.

4. Hyperfibrinolysis:
(1) Muamua: O le le lava o le fibrinolytic inhibitors i le tupuaga po'o le fa'ateleina o le gaioiga o le plasminogen e faigofie ona mafua ai le hyperfibrinolysis i fa'ama'i ogaoga o le ate, tumors, taotoga, ma manu'a;
(2) Maua: vaaia i le thrombosis, DIC, ma faʻamaʻi ate ogaoga (lona lua)

Fa'ateleina fa'ama'i o vaila'au o lo'o tafe i le toto, fa'ama'i e pei o le F VIII, FX, F XI, ma le F XII, fa'ama'i e puipuia ai le tino mai le fa'ama'i, tumo leaga, fa'ateleina o le tele o vaila'au e pei o le heparin, ma vaila'au e puipuia ai le lupus.

Fa'asinomaga: [1] Xia Wei, Chen Tingmei. Metotia Su'ega o le Hematologi Fa'afoma'i. Lomiga lona 6 [M]. Beijing. Fale Lomitusi a le Soifua Maloloina o Tagata. 2015